THE PURSER WELLNESS ENCYCLOPEDIA

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YouTubeAug 6, 2026

OVER-METHYLATION - Are Your B Vitamins Hurting You?

Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

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FacebookAug 5, 2026

Start gathering the information that could help you make more informed decisions about your wellness.

Start gathering the information that could help you make more informed decisions about your wellness. Your body has a story to tell. It is time to start listening. Find out more and discover the wellness help you have been looking for at

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FacebookAug 4, 2026

Feeling tired all the time is often dismissed as stress, aging, or a busy schedule.

Feeling tired all the time is often dismissed as stress, aging, or a busy schedule. But persistent fatigue can have many possible causes, including nutritional issues that may not be obvious from routine testing. A Cellular Micronutrient

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FacebookAug 1, 2026

What if your genes have been providing clues about your health your entire life?

What if your genes have been providing clues about your health your entire life? Most people spend years treating symptoms without ever asking why those symptoms exist in the first place. Genetic testing can provide valuable insight into

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