THE PURSER WELLNESS ENCYCLOPEDIA

Let’s explore “DHEA-S — lab reference”

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Gene referenceSep 23, 2026

COMT

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Makes an enzyme that helps break down catechol compounds, including some neurotransmitters. A common variant does not by itself explain mood, attention or stress tolerance. Also called: Catechol-O-Methyltransferase Catecholamines and sensit…

Gene referenceSep 23, 2026

CTH

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CTH helps make cysteine, one of the building blocks your body uses to make glutathione. Also called: Cystathionine Gamma-Lyase From homocysteine toward glutathione Dr. Purser places CTH in the sulfur-handling pathway that connects homocyste…

Gene referenceSep 23, 2026

DHFR

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DHFR helps reduce folic acid and dihydrofolate to tetrahydrofolate-related forms used in cellular metabolism. This is one part of the folate system, distinct from MTHFR and folate transport into cells. Also called: Dihydrofolate Reductase R…

Gene referenceSep 23, 2026

ESR1

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ESR1 encodes estrogen receptor alpha, which helps cells respond to estrogen. Receptor signaling is different from the amount of estrogen measured in blood. Also called: Estrogen Receptor 1 Estrogen signaling depends on the receptor ESR1 enc…

Gene referenceSep 23, 2026

FADS1

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Encodes an enzyme involved in fatty-acid metabolism. Also called: Fatty Acid Desaturase 1 / D5D The form of a fatty acid matters Dr. Purser teaches FADS genes as a conversion pathway. FADS1 participates in a delta-5 desaturase step in fatty…

Gene referenceSep 23, 2026

FADS2

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Encodes an enzyme involved in fatty-acid metabolism. Also called: Fatty Acid Desaturase 2 / D6D The form of a fatty acid matters Dr. Purser teaches FADS genes as a conversion pathway. FADS2 participates in a delta-6 desaturase step in fatty…

Gene referenceSep 23, 2026

FTO

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FTO is studied in relation to body weight and energy balance. Common variants can contribute to population-level differences in obesity susceptibility, alongside many other genes and environmental factors. Also called: Fat Mass and Obesity-…

Gene referenceSep 23, 2026

GAD2

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GAD2 helps make GABA, a chemical messenger, from glutamate. Also called: Glutamate Decarboxylase 2 Another part of the GABA system GAD2 helps make GABA from glutamate. GAD1 does a related job, but the two genes are different. Check the exac…

Gene referenceSep 23, 2026

GCLC

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GCLC helps make glutathione, an antioxidant your body produces. Also called: Glutamate-Cysteine Ligase Catalytic Subunit Making glutathione is a process Dr. Purser groups GCLC and GCLM as glutathione-synthesis machinery. GCLC supplies the c…

Gene referenceSep 23, 2026

GCLM

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GCLM helps regulate one of the steps your body uses to make glutathione. Also called: Glutamate-Cysteine Ligase Modifier Subunit Making glutathione is a process Dr. Purser groups GCLC and GCLM as glutathione-synthesis machinery. GCLM suppli…

Gene referenceSep 23, 2026

GDF5

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GDF5 encodes growth differentiation factor 5, a signaling protein involved in skeletal development, joint formation and cartilage biology. Its name does not mean a SNP measures the ability to build muscle. Also called: Growth Differentiatio…

Gene referenceSep 23, 2026

GGH

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GGH encodes gamma-glutamyl hydrolase, which removes glutamate residues from folate compounds. This affects folate handling and helps explain why folate metabolism includes retention and processing as well as intake. Also called: Gamma-Gluta…

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