THE PURSER WELLNESS ENCYCLOPEDIA
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What’s searchable?ALPL encodes tissue-nonspecific alkaline phosphatase, an enzyme important to bone and tooth mineralization and vitamin B6 metabolism. Persistently low alkaline phosphatase can deserve a different evaluation from a general nutrient deficiency.
How many health problems are being blamed on everything except the real cause? Vitamin B6 is one of the most overlooked nutrients in wellness conversations, yet it plays a critical role in everything from energy and mood to brain function
Homocysteine is nasty — but here’s the truth no one tells you. It doesn’t kill you directly — it triggers white blood cells to release IL-8 and MCP-1, causing inflammation, kidney failure, heart attacks, and strokes. Most doctors don’t even check it anymore, thinking there’s no fix. But there is. Whether from 17 genetic SNPs or 12 vitamin deficiencies (like B6 or B12), you can address it by supporting your body’s ability to convert homocysteine into glutathione.
Searchable captionsCopper is essential for life—it helps enzymes work, supports SOD1 for antioxidant defense, and even prepares iron to carry oxygen in the blood. But when copper builds up in the bloodstream instead of entering cells, it causes pain, tender points, and migraines. This often ties back to genes like CBS, NAT2, and glutathione-related SNPs that impair copper transport. The solution is supporting ceruloplasmin—the copper-binding protein—with targeted nutrients like B6, zinc, and NAC. That’s why Copper Balance was created: to move copper where it belongs and help symptoms finally improve. Visit PhysicianDesigned.com or Amazon for Copper Balance. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd
Searchable captionsRead matching passageDoctors have spent decades trying to lower homocysteine with B6, B12, folate, or $12,000/month injections. But it’s not the homocysteine doing the damage—it’s the IL-8 and MCP-1 cytokines it releases. That’s where glutathione (especially VARS or Glutaryl) changes the game. We’ve seen cytokine levels drop to zero—and symptoms vanish. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd
Searchable captionsRead matching passage🧬 After reviewing over 78,000 tests, Dr. Purser sees the same deficiencies over and over again—especially in fibro patients: Copper & zinc (often imbalanced): Glutathione, B6, B12 & folate, Glutamine, boron, molybdenum, And don’t forget mag
🧬 After reviewing over 78,000 tests, Dr. Purser sees the same deficiencies over and over again—especially in fibro patients: Copper & zinc (often imbalanced): Glutathione, B6, B12 & folate, Glutamine, boron, molybdenum, And don’t forget magnesium—a major cause of leg cramps and muscle pain. If you’re dealing with fibro, fatigue, or chronic pain, this list is where to start. The good news? It’s all fixable. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd
Searchable captionsRead matching passage🔥 High homocysteine doesn’t just cause strokes—it can cause widespread inflammation and pain that feels like arthritis. 🧬 Often tied to a B6 deficiency, and the only way to catch it early is through intracellular testing. Don’t wait.
🧬 If your NutraHacker shows a CBS or GGH SNP, check your homocysteine levels ASAP. High homocysteine often means you’re low in B6 (pyridoxine) — but don’t overdo it. Start slow with P5P and test first to avoid toxicity.
If you have MTHFR gene mutations like C677T or A1298C, you’re likely low in more than just B12 and folate. 🧬 We consistently see deficiencies in B6 (pyridoxine), glutamine, glutathione, and sometimes methionine—all key players in energy, de
There are several deficiencies I see again and again with my MTHFR patients, and it gets bad. B12, Folate, B6, Glutamine, Glutathione, and methionine. Treat these and make your bad MTHFR go away.
Homocysteine- one of the most inflammatory substances in the body - can’t be broken down and converted into Glutathione if you have this deficiency: B6. The transsulfuration pathway is broken if you don’t have sufficient B6 levels in your
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