Let’s explore “Bladder pain and cytokines”

Mast Cell Activation Syndrome (MCAS) often flares when oxidative stress is high, pushing mast cells to release histamine and inflammatory cytokines. Superoxide Dismutase (SOD) is your body’s first defense against that stress—neutralizing su

A post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.

A post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.

Copper is essential for life—it helps enzymes work, supports SOD1 for antioxidant defense, and even prepares iron to carry oxygen in the blood. But when copper builds up in the bloodstream instead of entering cells, it causes pain, tender p

PURSER WELLNESSCopper Overload In Body - What Can You Do?A conversation with Dr. Purser

Copper is essential for life—it helps enzymes work, supports SOD1 for antioxidant defense, and even prepares iron to carry oxygen in the blood. But when copper builds up in the bloodstream instead of entering cells, it causes pain, tender points, and migraines. This often ties back to genes like CBS, NAT2, and glutathione-related SNPs that impair copper transport. The solution is supporting ceruloplasmin—the copper-binding protein—with targeted nutrients like B6, zinc, and NAC. That’s why Copper Balance was created: to move copper where it belongs and help symptoms finally improve. Visit PhysicianDesigned.com or Amazon for Copper Balance. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants, gut and digestion.

PURSER WELLNESSIs Your Fibromyalgia Affected by High Homocysteine?A conversation with Dr. Purser

🧬 High homocysteine isn’t just a heart problem—it’s a major player in fibromyalgia. If you’ve got fibro symptoms, there’s a good chance your transsulfuration pathway is broken—often due to 17 different SNPs or 12 key nutrient deficiencies. That means your body can’t detox properly or convert homocysteine into glutathione, leading to inflammation, pain, and fatigue. Don’t just chase labs—fix the root cause. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Doctors have spent decades trying to lower homocysteine with B6, B12, folate, or $12,000/month injections. But it’s not the homocysteine doing the damage—it’s the IL-8 and MCP-1 cytokines it releases. That’s where glutathione (especially VA

PURSER WELLNESSTreating Homocysteine May Treat The WORLD!A conversation with Dr. Purser

Doctors have spent decades trying to lower homocysteine with B6, B12, folate, or $12,000/month injections. But it’s not the homocysteine doing the damage—it’s the IL-8 and MCP-1 cytokines it releases. That’s where glutathione (especially VARS or Glutaryl) changes the game. We’ve seen cytokine levels drop to zero—and symptoms vanish. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSGlutathione Treatment for Cystic Fibrosis?A conversation with Dr. Purser

Kids with cystic fibrosis often have high levels of inflammatory cytokines like IL-4, IL-5, IL-8, and IL-13, which damage the lungs. Research shows raising glutathione can lower these cytokines, yet most products don’t work. VARS Glutathione is a patented, functional form proven to get inside cells and reduce cytokine levels, offering real support for conditions like CF and beyond Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSMost Common Vitamin Deficiencies I See?A conversation with Dr. Purser

🧬 After reviewing over 78,000 tests, Dr. Purser sees the same deficiencies over and over again—especially in fibro patients: Copper & zinc (often imbalanced): Glutathione, B6, B12 & folate, Glutamine, boron, molybdenum, And don’t forget magnesium—a major cause of leg cramps and muscle pain. If you’re dealing with fibro, fatigue, or chronic pain, this list is where to start. The good news? It’s all fixable. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

🧬 Dealing with Crohn’s or ulcerative colitis? These conditions are heavily influenced by inflammatory cytokines your body makes during stress and poor autophagy. Research shows that glutathione can help regulate and calm those cytokines—but