Understanding the Genetic Basis and Implications of PEMT Variants
A subscriber post from Purser Wellness on Substack, covering genetics and methylation, gut and digestion.
THE PURSER WELLNESS ENCYCLOPEDIA
5 chapters, at your pace
245 resources45 matching listings grouped; alternative sources stay available.
What’s searchable?A subscriber post from Purser Wellness on Substack, covering genetics and methylation, gut and digestion.
Dan Purser MD interviews a patient with a brutal sarcoidosis case involving sky-high SIL2R cytokines, GI sarcoid, heart damage, and years of being dismissed by doctors. After spleen removal, repeated ER visits, and nitroglycerin dependence, he finally found answers. Learn how cytokine testing and the VARS Trio (Glutathione + SOD + Catalase) led to rapid improvement — going from bedridden fear to playing with grandkids in just weeks. This episode highlights the power of root-cause medicine for complex inflammatory conditions and offers hope for those who feel lost in the system. Perfect for listeners dealing with sarcoidosis, chronic inflammation, autoimmune issues, or cytokine-related symptoms. #Sarcoidosis #Cytokines #VARS #PurserWellness #ChronicIllnessRecovery Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd
Searchable captionsWhat if inflammation isn't the problem—it's the warning sign? Too many people are told to simply live with chronic inflammation, masking symptoms while the underlying triggers continue unchecked. Fatigue. Brain fog. Joint discomfort. Dige
Could your gut issues have nothing to do with what you're eating? What if the real problem is a hidden nutrient pathway most people—and even many health professionals—never think to investigate? Purser Wellness Coach Jackson Larkin breaks
What if your fatty liver isn't just about diet, weight, or alcohol? What if the real issue is hidden in your genetics? One of the most overlooked contributors to fatty liver may be variations in the PEMT gene. This pathway plays a critica
🙏 A Big Thank You to Our Purser Wellness Family! Hey everyone! To all of you who found us and followed our Purser Wellness Facebook page. Thank you! We’re so grateful you’ve stuck with us, especially while we didn’t have full access to our
What if your fatigue, inflammation, digestive issues, or chronic discomfort aren't random—and what if the answers have been available all along? Purser Wellness Coach Jackson Larkin explains why CMA testing is challenging conventional appr
A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants, gut and digestion.
A post from Purser Wellness on Substack, covering genetics and methylation, gut and digestion, mind, mood, and sleep.
Hi, I’m Dr. Dan Purser. For too long, autism has been treated as a mystery with only symptom management. In this episode, I break down what I’ve seen consistently in practice: the real root cause behind many cases on the spectrum. It starts with genetic variants (especially MTHFR and related SNPs) that break the transsulfuration pathway. When kids can’t efficiently convert homocysteine into glutathione, they lose their ability to detox heavy metals and environmental toxins. The result is chronic inflammation, oxidative stress, and developmental challenges. The good news? Once we identify these biochemical and genetic imbalances through proper testing, we can intervene at the root with targeted support — restoring methylation, rebuilding glutathione function, and giving the body what it needs to heal. This isn’t theory. It’s the Purser Method® in action. If you’re a parent searching for real answers instead of just labels, this episode is for you. The root cause has been solved. Now let’s talk solutions.
Searchable captionsMost people have never heard of PEMT deficiency—but it could be the missing link behind stubborn fatty liver, low energy, brain fog, and why standard health advice isn’t working. The real controversy? Many people are treating symptoms wh
Fatty liver isn’t just about food, alcohol, or bad habits. For many people, it may be a hidden PEMT problem no one is talking about. If your body can’t process fats the way it should, no amount of “healthy living” will fix the root cause.
Search looks for your words in titles, descriptions, available articles, learning guides, and video captions when available. The closest matches appear first. Duplicate posts are grouped, with links to other places you can read or watch them. Books, chapters, and reports have topic guides here; the original files and full book text are not available in this encyclopedia. Subscriber posts include a title and public summary; open Substack to read the full post.