Let’s explore “Pulmonary fibrosis: inflammation, repair, and scarring”

NQO1 is the gene name for NAD(P)H Quinone Oxidoreductase 1. Learn what a specific result could mean and what to ask about it.

NR3C2 encodes the mineralocorticoid receptor, which responds to hormones such as aldosterone and helps regulate salt and fluid balance. It is distinct from the NR3C1 glucocorticoid receptor.

Makes an enzyme involved in producing phosphatidylcholine, a component of cell membranes. Genetic findings alone do not establish a choline deficiency.

PON1 is discussed in relation to how the body handles some compounds and protects certain fats.

SHMT1 connects serine and glycine with folate chemistry.

SOD1 helps convert superoxide inside cells as part of the body’s antioxidant defenses.

SOD2 works in mitochondria as part of the body’s antioxidant defenses.

SOD3 works outside cells as part of the body’s antioxidant defenses.

TCN2 helps carry vitamin B12 in the body. A gene result alone cannot tell you your B12 status.

Understand why Dr. Purser teaches glutathione, SOD and catalase as a connected antioxidant team.

Encodes the reduced folate carrier, a protein involved in transporting folates into cells.

CCL3 encodes MIP-1 alpha, a chemokine involved in attracting and activating immune cells. It is related to CCL4, or MIP-1 beta, but the two genes and proteins are distinct.