Let’s explore “PAI-1 4G/5G & homocysteine”

If your body can’t convert homocysteine to glutathione, bad things happen—especially inflammation and stroke risk. ⚠️ High homocysteine is a major driver of cardiovascular issues, and it’s often missed. If you know someone young who’s had a

🚨 Homocysteine is nasty — but here’s the truth no one tells you. It doesn’t kill you directly — it triggers white blood cells to release IL-8 and MCP-1, causing inflammation, kidney failure, heart attacks, and strokes. Most doctors don’t ev

Make sure to check out this new post! Critical for understanding the connection of Homocysteine and Glutathione, how the two are interconnected and how you can minimize the effects of high Homocysteine. https://danpursermd.substack.com/p/

What’s transsulfuration? It’s your body’s way of turning inflammatory homocysteine into glutathione, your master antioxidant. 🧬 If your glutathione is low, this pathway (often tied to CBS SNPs) might not be working—and it depends heavily on

A subscriber post from Purser Wellness on Substack, covering inflammation and antioxidants.

MTHFR plagues MILLIONS of people, and the top symptom is FATIGUE. Gene SNPs related to Homocysteine also cause widespread INFLAMMATION causing you to suffer more. VARS Glutathione and MTHFR Daily will become your BEST FRIENDS in managing MT

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.

A subscriber post from Purser Wellness on Substack, covering genetics and methylation, inflammation and antioxidants.

If you’ve been told you have the MTRR gene mutation and struggle with fatigue, depression, or high homocysteine, this might be your missing link. MTRR mutations can impair your body’s ability to make SAMe (S-adenosyl methionine)—a critical