Renin / plasma renin activity — lab reference
In the reference guideDirect renin and plasma renin activity are not interchangeable.
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What’s searchable?Direct renin and plasma renin activity are not interchangeable.
Screening cutoff depends on units, method, medications, potassium, and collection protocol.
RBC, plasma, and cellular assays are not interchangeable.
Normal <100; prediabetes 100-125; diabetes ≥126 on confirmatory testing unless unequivocal hyperglycemia.
Diabetes may be diagnosed at ≥200 with classic symptoms or hyperglycemic crisis.
Recent supplementation can elevate; very high values may be clinically relevant.
Highly preanalytic-sensitive. Fasting, processing, and recent intake matter.
Sodium intake, posture, potassium, time, medications, and renin method are essential.
How you sit or lie down for the sample, and stress during collection, can affect this result. Use the cutoff from the lab that ran your test.
The method can change the result; ask what clinical question the test is meant to answer and whether a repeat would help.
Ask your clinician to use performing-lab range and trend with C4/CH50 and disease activity.
Ask your clinician to specify whole blood, RBC, plasma, or intracellular method. Preanalytic handling is critical.
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