Total iron-binding capacity (TIBC) — lab reference
In the reference guideAsk your clinician to read this result with iron, transferrin saturation, and ferritin.
THE PURSER WELLNESS ENCYCLOPEDIA
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What’s searchable?Ask your clinician to read this result with iron, transferrin saturation, and ferritin.
Affected by thyroid-binding globulin, pregnancy, estrogen, and medications.
Affected by binding proteins and nonthyroidal illness.
No universal wellness target. Ask your clinician to read this result with B12, folate, B6, kidney, thyroid, genetics, and medications.
Correct for albumin when appropriate or measure ionized calcium.
Fasting, Gilbert syndrome, hemolysis, and liver disease may alter result.
Ask your clinician to review albumin, globulin, and electrophoresis when indicated.
Screening measure, not a stand-alone treatment target.
Morning fasting collection is preferred when practical. Day-to-day variation is substantial.
<10 severe deficiency; 10-19 mild-moderate deficiency. Toxicity assessment requires clinical context.
Morning collection preferred for men. Method and age matter; confirm unexpected low values.
Estrogen, thyroid, liver disease, insulin resistance, age, and medications affect SHBG.
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