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Gene & pathway reference · FROM DR. PURSER’S TEACHING

CCL4

CCL4 encodes MIP-1 beta, a chemokine involved in attracting immune cells. It participates in a recruitment network that includes CCL2, CXCL8 and related chemokines.

Based on teaching by Dan Purser, MD. How we prepare these guides

Updated Sep 23, 2026 · Educational reference

THE TEACHING CONNECTION

MIP-1 beta and overlapping recruitment signals

MIP-1 beta and overlapping recruitment signals

CCL4 encodes MIP-1 beta, a chemokine involved in attracting immune cells. It participates in a recruitment network that includes CCL2, CXCL8 and related chemokines.

Putting the pieces together

Dr. Purser connects CCL4 with late-phase allergic activity and with the vascular inflammatory network discussed in his homocysteine model. The updated panel removes a previously misassigned marker, rs11079929; it should not be treated as a CCL4 result. The teaching connection remains useful without that erroneous mapping.

Where the VARS Triad and MTHFR Daily fit

If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and the VARS Triad: VARS Glutathione, VARS SOD, and VARS Catalase. He gives glutathione a central place in his approach to antioxidant support.

A gene result alone cannot tell you that you need these products or that they will treat a condition. Review your current results, medicines, goals, and tolerance with your clinician before choosing a product or dose.

A question to bring to your visit

Has the gene-to-variant mapping been checked, and what clinical allergic or vascular findings are relevant?

Variant lookup

These names can help you find an entry on your original genetic report. Seeing a name here does not tell you whether it affects your health or whether you need treatment.

Names you may see

MIP-1 beta · MIP-1β