← Genes & pathways

Gene & pathway reference · FROM DR. PURSER’S TEACHING

IL13

IL13 encodes interleukin-13, a cytokine involved in Th2 immune responses, mucus-related processes and tissue remodeling. It overlaps with some IL-4 functions but is not the same signal.

Based on teaching by Dan Purser, MD. How we prepare these guides

Updated Sep 23, 2026 · Educational reference

THE TEACHING CONNECTION

Allergic signaling and tissue responses

Allergic signaling and tissue responses

IL13 encodes interleukin-13, a cytokine involved in Th2 immune responses, mucus-related processes and tissue remodeling. It overlaps with some IL-4 functions but is not the same signal.

Putting the pieces together

Dr. Purser places IL-13 in the allergy and Th2 part of his panel. That directs attention to symptoms such as airway or nasal allergy patterns and their timing, rather than assuming every cytokine-related symptom has the same cause. A variant alone does not establish asthma or an allergy.

Where the VARS Triad and MTHFR Daily fit

If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and the VARS Triad: VARS Glutathione, VARS SOD, and VARS Catalase. He gives glutathione a central place in his approach to antioxidant support.

A gene result alone cannot tell you that you need these products or that they will treat a condition. Review your current results, medicines, goals, and tolerance with your clinician before choosing a product or dose.

A question to bring to your visit

Are symptoms and testing consistent with a Th2 allergic pattern or a different problem?

Variant lookup

These names can help you find an entry on your original genetic report. Seeing a name here does not tell you whether it affects your health or whether you need treatment.

rs1800925rs20541rs1295686

Names you may see

IL-13 · Interleukin 13

Now hear the conversation.

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PURSER WELLNESSKids with cystic fibrosis often have high levels of inflammatory cytokines like IL-4, IL-5, IL-8, and IL-13, which…A conversation with Dr. Purser
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Kids with cystic fibrosis often have high levels of inflammatory cytokines like IL-4, IL-5, IL-8, and IL-13, which…

Kids with cystic fibrosis often have high levels of inflammatory cytokines like IL-4, IL-5, IL-8, and IL-13, which damage the lungs. Research shows raising glutathione can lower these cytokines, yet most products don’t work. VARS Glutathion

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PURSER WELLNESSKids with cystic fibrosis often have high levels of inflammatory cytokines like IL-4, IL-5, IL-8, and IL-13, which…A conversation with Dr. Purser
FacebookSep 22, 2025

Kids with cystic fibrosis often have high levels of inflammatory cytokines like IL-4, IL-5, IL-8, and IL-13, which…

Kids with cystic fibrosis often have high levels of inflammatory cytokines like IL-4, IL-5, IL-8, and IL-13, which damage the lungs. Research shows raising glutathione can lower these cytokines, yet most products don’t work. VARS Glutathion

Cytokines