THE TEACHING CONNECTION
Folate has several working forms
Folate has several working forms
Dr. Purser includes MTHFD1 among genes involved in folate interconversion. The lesson is that folate participates in several reactions and exists in more than one working form; a pathway review should not stop at the word “folate” on a bottle.
Putting the pieces together
MTHFD1 connects with other folate genes such as MTHFR, SHMT1 and SLC19A1. What matters for you is the full picture: your current findings, the vitamins you take and how you tolerate them. A named gene does not create a separate supplement requirement.
Where the VARS Triad and MTHFR Daily fit
If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and the VARS Triad: VARS Glutathione, VARS SOD, and VARS Catalase. He gives glutathione a central place in his approach to antioxidant support.
A gene result alone cannot tell you that you need these products or that they will treat a condition. Review your current results, medicines, goals, and tolerance with your clinician before choosing a product or dose.
A question to bring to your visit
Which part of the folate pathway is being discussed, and what current evidence makes it relevant?
Reading your own results
Bring your original report, current results, health history, and medicines to your visit. This information can help you ask questions, but it cannot diagnose a condition or choose a supplement dose for you.
Variant lookup
These names can help you find an entry on your original genetic report. Seeing a name here does not tell you whether it affects your health or whether you need treatment.
Names you may see
Methylenetetrahydrofolate Dehydrogenase 1
EXPLORE WITH YOUR CARE TEAM
Supplements to explore
Compare the products below, including their ingredients and available forms. Your care team can help you choose one or more options for your needs.
COMPARE YOUR OPTIONS
Methylation support
Dr. Purser discusses these supplements in relation to MTHFD1.
MTHFR Daily and Hydroxy B12 + Folinic Acid are alternatives. Your folate, vitamin B12, and genetic results can help your clinician choose between them.
CAPSULES & LIQUID
Glutathione options
Dr. Purser discusses these supplements in relation to MTHFD1.
Some genetic results may make these options more relevant to you. Review your full genetic report with your clinician before choosing a supplement.
SUPPLEMENT OPTIONS
VARS SOD
Explore supplements Dr. Purser discusses alongside inflammation and antioxidant support.
Ask your clinician how this option fits your results and current medicines.
SUPPLEMENT OPTIONS
VARS Catalase Support
Explore supplements Dr. Purser discusses alongside inflammation and antioxidant support.
Ask your clinician how this option fits your results and current medicines.
Tell your care team which supplements and medicines you already take. Check the product page for current ingredients, prices, and availability.
