Genomic imprinting and growth: understanding BWS

Understand the connection

Genomic imprinting describes how some genes are regulated differently depending on which parent contributed them. Beckwith-Wiedemann syndrome is one example involving growth-related imprinting.

Follow the pathway

Dr. Purser’s genetics teaching distinguishes DNA sequence variation from epigenetic regulation. This condition involves a specific growth-control region and is different from common MTHFR variants or a general methylation supplement discussion.

Bring these questions to your visit

Ask a clinical genetics team about the exact diagnosis, developmental needs, and recommended surveillance. A consumer gene panel does not establish an imprinting disorder.