Let’s explore “Homocysteine, folate transport, and uric acid”

A post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.

High homocysteine signals a broken transsulfuration pathway, leaving you unable to detox or convert it into glutathione. This shows up in conditions like PCOS and fibromyalgia, where patients often struggle with inflammation, pain, and even

A post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.

High homocysteine often shows up first as widespread inflammation—pain all over, poor circulation, or even early warning signs of cardiovascular problems like stroke and heart attack. The best way to know for sure is through testing: a bloo

Homocysteine is a natural molecule your body makes, but when levels get too high it drives massive inflammation by triggering cytokine release. For some people, genetics or deficiencies cause a “fixed homocysteine rate,” meaning diet and vi

PURSER WELLNESSWhat Is A Fixed Homocysteine Rate?A conversation with Dr. Purser

Homocysteine is a natural molecule your body makes, but when levels get too high it drives massive inflammation by triggering cytokine release. For some people, genetics or deficiencies cause a “fixed homocysteine rate,” meaning diet and vitamins alone won’t lower it. In those cases, the only real way to balance it is by supporting the pathway that converts homocysteine into glutathione. That’s why reduced, stable glutathione—like VARS Glutathione—is essential, because most products are oxidized and useless by the time you take them. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

TMG (trimethylglycine) can sometimes lower homocysteine—but only if it’s not caused by genetics. When homocysteine is high from genetic SNPs, TMG won’t fix it, and restrictive “low-methionine diets” are both harmful and outdated. The real s

A post from Purser Wellness on Substack, covering genetics and methylation, inflammation and antioxidants.

Your body’s ability to detox depends on one critical pathway—turning homocysteine into glutathione. But for millions with MTHFR or other genetic SNPs, this process is broken, leaving them vulnerable to toxins, inflammation, and cytokine sto

A post from Purser Wellness on Substack, covering genetics and methylation, inflammation and antioxidants.

🚨 Homocysteine might be the most dangerous thing your doctor isn’t checking. It’s been linked to kidney failure, dialysis, hypertension, strokes, heart attacks, melanoma, and renal cancer. But it’s not the homocysteine itself—it’s the cytok

PURSER WELLNESSWhat is the true harm of high homocysteine?A conversation with Dr. Purser

🚨 Homocysteine might be the most dangerous thing your doctor isn’t checking. It’s been linked to kidney failure, dialysis, hypertension, strokes, heart attacks, melanoma, and renal cancer. But it’s not the homocysteine itself—it’s the cytokines it triggers, like IL-8 and MCP-1, that do the damage. And if you’ve got any of the 17 key genetic SNPs, you’re at serious risk. You may not be able to lower homocysteine directly—but you can shut down those cytokines with the right nutrients and VARS Glutathione. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd