GGH encodes gamma-glutamyl hydrolase, which removes glutamate residues from folate compounds. This affects folate handling and helps explain why folate metabolism includes retention and processing as well as intake.
Also called: Gamma-Gluta…
GPX1 helps cells use glutathione to handle peroxides.
Also called: Glutathione Peroxidase 1
Glutathione has enzyme partners
Dr. Purser teaches the glutathione peroxidase family alongside selenium and antioxidant support. GPX1 helps illustra…
GPX3 helps use glutathione in peroxide defense outside cells.
Also called: Glutathione Peroxidase 3
Glutathione has enzyme partners
Dr. Purser teaches the glutathione peroxidase family alongside selenium and antioxidant support. GPX3 helps …
GPX4 helps protect cell membranes from certain peroxides.
Also called: Glutathione Peroxidase 4
Glutathione has enzyme partners
Dr. Purser teaches the glutathione peroxidase family alongside selenium and antioxidant support. GPX4 helps illu…
GSR encodes glutathione reductase. It uses reducing power from NADPH to help convert oxidized glutathione back to reduced glutathione, allowing this antioxidant system to be reused.
Also called: Glutathione Reductase
Recycling used glutathi…
HDC is the gene name for Histidine Decarboxylase. Learn what a specific result could mean and what to ask about it.
Also called: Histidine Decarboxylase
Histamine production is one part of the circuit
HDC is involved in the enzyme step conv…
HRH1 is the gene name for Histamine Receptor H1. Learn what a specific result could mean and what to ask about it.
Also called: Histamine Receptor H1
Receiving the histamine signal
The Purser genetics reference places HRH1 in the histamine-…
MTHFD1 helps move folate between forms used for different jobs in the body.
Also called: Methylenetetrahydrofolate Dehydrogenase 1
Folate has several working forms
Dr. Purser includes MTHFD1 among genes involved in folate interconversion. T…
The homocysteine chapters include MTHFD1L in the wider folate-related genetic map.
Also called: Methylenetetrahydrofolate Dehydrogenase 1-Like
A mitochondrial contribution to one-carbon metabolism
The homocysteine chapters include MTHFD1L i…
Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.
Also called: Methylenetetrahydrofolate Reductase, C677T, A1298C…
Helps maintain the activity of methionine synthase, connecting B12-related chemistry with homocysteine metabolism.
Also called: Methionine Synthase Reductase
Keeping the remethylation system working
Dr. Purser teaches MTRR alongside MTR bec…
NAT2 encodes N-acetyltransferase 2, which helps process certain drugs and other compounds. Combinations of variants can influence acetylation status; one SNP usually does not tell the entire story.
Also called: N-Acetyltransferase 2
Acetyla…
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