GSTT1 helps your body use glutathione to process some compounds.
Also called: Glutathione S-Transferase Theta 1, GSTT
Using glutathione in conjugation
GSTT1 belongs to the glutathione transferase family. These enzymes use glutathione in con…
HLA-DQA1 contributes to an HLA-DQ protein that presents antigen fragments to CD4 T cells. HLA-DQ function depends on pairing with an HLA-DQB chain, so an isolated marker is not a complete HLA type.
Also called: HLADQA1, Human Leukocyte Anti…
MAOA helps break down some chemical messengers. A gene result cannot predict a mood or behavior.
Also called: MAO-A, Monoamine Oxidase A
Neurotransmitter breakdown in context
Dr. Purser places MAOA in the neurotransmitter-breakdown part of …
Makes the methionine synthase enzyme, which uses vitamin B12 in the conversion of homocysteine to methionine.
Also called: Methionine Synthase
The B12-dependent step
In Dr. Purser’s teaching map, MTR is the B12-dependent step that converts …
NAT2 encodes N-acetyltransferase 2, which helps process certain drugs and other compounds. Combinations of variants can influence acetylation status; one SNP usually does not tell the entire story.
Also called: N-Acetyltransferase 2
Acetyla…
NR3C1 encodes the glucocorticoid receptor, which helps tissues respond to cortisol and glucocorticoid medicines. Receptor genetics and measured cortisol levels answer different questions.
Also called: Nuclear Receptor Subfamily 3 Group C Me…
NR3C2 encodes the mineralocorticoid receptor, which responds to hormones such as aldosterone and helps regulate salt and fluid balance. It is distinct from the NR3C1 glucocorticoid receptor.
Also called: Mineralocorticoid Receptor / Nuclear…
NTRK2 encodes TrkB, a receptor involved in responding to neurotrophic signals such as BDNF. These signals support nervous-system function and plasticity. NTRK2 is not a phosphatidylserine absorption transporter.
Also called: Neurotrophic Re…
Makes an enzyme involved in producing phosphatidylcholine, a component of cell membranes. Genetic findings alone do not establish a choline deficiency.
Also called: Phosphatidylethanolamine N-Methyltransferase, choline, phosphatidylcholine
…
PON1 is discussed in relation to how the body handles some compounds and protects certain fats.
Also called: Paraoxonase 1
A different part of antioxidant handling
PON1 appears in Dr. Purser’s redox and conversion teaching alongside GST and…
TCN2 helps carry vitamin B12 in the body. A gene result alone cannot tell you your B12 status.
Also called: Transcobalamin II
B12 must be carried as well as consumed
TCN2 appears in Dr. Purser’s homocysteine and methylation map because it c…
VDR encodes the vitamin D receptor, which helps regulate gene activity in response to active vitamin D. A receptor variant does not by itself mean receptors are absent or that the blood vitamin D level is low.
Also called: Vitamin D Recepto…
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