THE PURSER WELLNESS ENCYCLOPEDIA

Let’s explore “Sjögren’s syndrome and immune signaling”

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Gene referenceSep 23, 2026

GSTT1

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GSTT1 helps your body use glutathione to process some compounds. Also called: Glutathione S-Transferase Theta 1, GSTT Using glutathione in conjugation GSTT1 belongs to the glutathione transferase family. These enzymes use glutathione in con…

Gene referenceSep 23, 2026

HLA-DQA1

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HLA-DQA1 contributes to an HLA-DQ protein that presents antigen fragments to CD4 T cells. HLA-DQ function depends on pairing with an HLA-DQB chain, so an isolated marker is not a complete HLA type. Also called: HLADQA1, Human Leukocyte Anti…

Gene referenceSep 23, 2026

MAOA

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MAOA helps break down some chemical messengers. A gene result cannot predict a mood or behavior. Also called: MAO-A, Monoamine Oxidase A Neurotransmitter breakdown in context Dr. Purser places MAOA in the neurotransmitter-breakdown part of …

Gene referenceSep 23, 2026

MTR

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Makes the methionine synthase enzyme, which uses vitamin B12 in the conversion of homocysteine to methionine. Also called: Methionine Synthase The B12-dependent step In Dr. Purser’s teaching map, MTR is the B12-dependent step that converts …

Gene referenceSep 23, 2026

NAT2

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NAT2 encodes N-acetyltransferase 2, which helps process certain drugs and other compounds. Combinations of variants can influence acetylation status; one SNP usually does not tell the entire story. Also called: N-Acetyltransferase 2 Acetyla…

Gene referenceSep 23, 2026

NR3C1

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NR3C1 encodes the glucocorticoid receptor, which helps tissues respond to cortisol and glucocorticoid medicines. Receptor genetics and measured cortisol levels answer different questions. Also called: Nuclear Receptor Subfamily 3 Group C Me…

Gene referenceSep 23, 2026

NR3C2

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NR3C2 encodes the mineralocorticoid receptor, which responds to hormones such as aldosterone and helps regulate salt and fluid balance. It is distinct from the NR3C1 glucocorticoid receptor. Also called: Mineralocorticoid Receptor / Nuclear…

Gene referenceSep 23, 2026

NTRK2

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NTRK2 encodes TrkB, a receptor involved in responding to neurotrophic signals such as BDNF. These signals support nervous-system function and plasticity. NTRK2 is not a phosphatidylserine absorption transporter. Also called: Neurotrophic Re…

Gene referenceSep 23, 2026

PEMT

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Makes an enzyme involved in producing phosphatidylcholine, a component of cell membranes. Genetic findings alone do not establish a choline deficiency. Also called: Phosphatidylethanolamine N-Methyltransferase, choline, phosphatidylcholine …

Gene referenceSep 23, 2026

PON1

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PON1 is discussed in relation to how the body handles some compounds and protects certain fats. Also called: Paraoxonase 1 A different part of antioxidant handling PON1 appears in Dr. Purser’s redox and conversion teaching alongside GST and…

Gene referenceSep 23, 2026

TCN2

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TCN2 helps carry vitamin B12 in the body. A gene result alone cannot tell you your B12 status. Also called: Transcobalamin II B12 must be carried as well as consumed TCN2 appears in Dr. Purser’s homocysteine and methylation map because it c…

Gene referenceSep 23, 2026

VDR

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VDR encodes the vitamin D receptor, which helps regulate gene activity in response to active vitamin D. A receptor variant does not by itself mean receptors are absent or that the blood vitamin D level is low. Also called: Vitamin D Recepto…

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