…nd adenosine. This adds the SAM/SAH balance to Dr. Purser’s methylation map.
Putting the pieces together
AHCY connects to the balance of molecules involved in methylation, which is more than a question of folate intake. Rare inherited AHCY …
…s homocysteine back to methionine. This helps explain why a methylation discussion should include B12 as well as folate, and why adding more folate alone does not answer every question.
Putting the pieces together
MTRR helps keep the MTR en…
…y alone.
Putting the pieces together
His wider map connects methylation with downstream sulfur handling and glutathione production. Learning the connection helps you distinguish raw materials, enzyme cofactors and current laboratory finding…
…l as consumed
TCN2 appears in Dr. Purser’s homocysteine and methylation map because it concerns the transport of B12. The teaching distinction is between eating or supplementing a vitamin, transporting it, and using it in an enzyme reaction…
…r can move toward cysteine. The recycling route is called remethylation. The route toward cysteine is called transsulfuration.
Folate and B12 help with one recycling route. Betaine, which can come from choline, helps with another. CBS and …
…eine, and Cytokines These physicians know almost zero about methylation or the FDA and HHS-approved intracellular micronutrient testing we use with our patients. (Yes, targeted vitamin deficiencies are often the hidden cause of the chronic …
…ongside B12 absorption, Intrinsic factor receptor activity, Methylation, Folate metabolism. These are topics to explore, not a diagnosis or a measurement of how the pathway works in your body.
Understanding a result
A gene name is only a st…
…3 discussed alongside Folate transport, Placental function, Methylation, Folate metabolism, PCOS, Insulin/glucose regulation, Hormone metabolism. These are topics to explore, not a diagnosis or a measurement of how the pathway works in your…
…rder is different from an acquired nutrient deficiency or a methylation result.
Bring these questions to your visit
Ask how the diagnosis has been confirmed and what specialist bowel care is needed. Genetic questions can support counseling…
…uch as C677T and A1298C can influence folate metabolism and methylation.
Stop blaming yourself.
Start understanding the biology.
Support your nutrition.
Support methylation when appropriate.
Prioritize protein, fiber, and healthy fa…
…cal pathways involved in areas such as nutrient metabolism, methylation, and other cellular processes.
Understanding those variations can give you and your healthcare team additional information to consider when making personalized wellne…
…r look.
MTHFR variants can influence folate metabolism and methylation, two processes involved in many functions throughout the body.
That is exactly why personalized health matters.
Your genes may provide clues.
Your symptoms provide c…
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