THE PURSER WELLNESS ENCYCLOPEDIA

Let’s explore “MTHFR, homocysteine, and immune signals”

Explore this topic as a step-by-step interactive map.MTHFR, the citric acid cycle & ATP
A RELATED COURSEYour MTHFR starting point

5 chapters, at your pace

Explore the course
Explore all 4 matching courses

959 resources for your curiosity185 matching listings grouped; alternative sources stay available.

What’s searchable?
InstagramDec 5, 2025

Most chronic inflammation, gut issues, and detox problems aren’t aging or bad luck — they’re methylation disorders…

Some search terms matched

Most chronic inflammation, gut issues, and detox problems aren’t aging or bad luck — they’re methylation disorders your doctor probably ignores. MTHFR and homocysteine matter more than mainstream medicine admits, and the research is about t

Also listed on FacebookFacebook listing
InstagramNov 13, 2025

Let’s Talk About MTHFR — The Gene That Impacts Your Energy

Some search terms matched

Let’s Talk About MTHFR — The Gene That Impacts Your Energy If you’re constantly tired no matter how much you rest, your MTHFR gene may be part of the reason. MTHFR (Methylenetetrahydrofolate Reductase) is a genetic SNP—a small DNA variation

Also listed on FacebookFacebook listing
YouTubeOct 23, 2025

What Is Genetic Testing?

Some search terms matched

Genetic testing has only been around for about 20 years, since the Human Genome Project made it possible to identify thousands of SNPs (gene variations) linked to disease and health issues. While gene editing with tools like CRISPR may be a future reality, for now the best way to “work around” your genes is by supplementing with the right vitamins, minerals, and amino acids. That’s exactly what the DRP Genetics test does—focusing on SNPs like MTHFR, PEMT, and others tied to homocysteine, gut, and brain health—so you can take preventative steps against even serious conditions like dementia and Alzheimer’s. Reach to my office with any questions on testing to get started! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Searchable captionsRead matching passage
InstagramOct 21, 2025

MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes…

Some search terms matched

MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialize

Also listed on FacebookFacebook listing
InstagramOct 4, 2025

Homocysteine is a natural molecule your body makes, but when levels get too high it drives massive inflammation by…

Some search terms matched

Homocysteine is a natural molecule your body makes, but when levels get too high it drives massive inflammation by triggering cytokine release. For some people, genetics or deficiencies cause a “fixed homocysteine rate,” meaning diet and vi

Also listed on FacebookFacebook listing
YouTubeOct 4, 2025

What Is A Fixed Homocysteine Rate?

Some search terms matched

Homocysteine is a natural molecule your body makes, but when levels get too high it drives massive inflammation by triggering cytokine release. For some people, genetics or deficiencies cause a “fixed homocysteine rate,” meaning diet and vitamins alone won’t lower it. In those cases, the only real way to balance it is by supporting the pathway that converts homocysteine into glutathione. That’s why reduced, stable glutathione—like VARS Glutathione—is essential, because most products are oxidized and useless by the time you take them. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Searchable captions
InstagramOct 3, 2025

Glutathione is called the “master antioxidant” because it protects every cell in your body from oxidative damage,…

Some search terms matched

Glutathione is called the “master antioxidant” because it protects every cell in your body from oxidative damage, supports detox, and reduces inflammation. People with high homocysteine or MTHFR gene variants often can’t recycle glutathione

Also listed on FacebookFacebook listing
InstagramSep 30, 2025

TMG (trimethylglycine) can sometimes lower homocysteine—but only if it’s not caused by genetics. When homocysteine…

Some search terms matched

TMG (trimethylglycine) can sometimes lower homocysteine—but only if it’s not caused by genetics. When homocysteine is high from genetic SNPs, TMG won’t fix it, and restrictive “low-methionine diets” are both harmful and outdated. The real s

Also listed on FacebookFacebook listing
YouTubeSep 30, 2025

TMG A Viable Option For Homocysteine?

Some search terms matched

TMG (trimethylglycine) can sometimes lower homocysteine—but only if it’s not caused by genetics. When homocysteine is high from genetic SNPs, TMG won’t fix it, and restrictive “low-methionine diets” are both harmful and outdated. The real solution lies in addressing deficiencies and genetics directly. Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Searchable captions

Search looks for your words in titles, descriptions, available articles, learning guides, and video captions when available. The closest matches appear first. Duplicate posts are grouped, with links to other places you can read or watch them. Books, chapters, and reports have topic guides here; the original files and full book text are not available in this encyclopedia. Subscriber posts include a title and public summary; open Substack to read the full post.