Dr. Purser and Justace discuss how genetics often reveal two major patterns in patients: either serious gut and liver issues like SIBO, pancreatitis, or colitis, or inflammatory problems tied to homocysteine and PEMT mutations. Sometimes pa
Dr. Purser and Justace discuss how genetics often reveal two major patterns in patients: either serious gut and liver issues like SIBO, pancreatitis, or colitis, or inflammatory problems tied to homocysteine and PEMT mutations. Sometimes patients suffer from both, which can lead to severe long-term complications like cancer, heart attacks, or strokes. While genetics isn’t the full answer, it provides critical insight into why these problems develop and how to intervene early.
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Genetic testing has only been around for about 20 years, since the Human Genome Project made it possible to identify thousands of SNPs (gene variations) linked to disease and health issues. While gene editing with tools like CRISPR may be a future reality, for now the best way to “work around” your genes is by supplementing with the right vitamins, minerals, and amino acids. That’s exactly what the DRP Genetics test does—focusing on SNPs like MTHFR, PEMT, and others tied to homocysteine, gut, and brain health—so you can take preventative steps against even serious conditions like dementia and Alzheimer’s. Reach to my office with any questions on testing to get started!
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MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialize
Copper is essential for life—it helps enzymes work, supports SOD1 for antioxidant defense, and even prepares iron to carry oxygen in the blood. But when copper builds up in the bloodstream instead of entering cells, it causes pain, tender points, and migraines. This often ties back to genes like CBS, NAT2, and glutathione-related SNPs that impair copper transport. The solution is supporting ceruloplasmin—the copper-binding protein—with targeted nutrients like B6, zinc, and NAC. That’s why Copper Balance was created: to move copper where it belongs and help symptoms finally improve. Visit PhysicianDesigned.com or Amazon for Copper Balance.
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
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Glutathione is called the “master antioxidant” because it protects every cell in your body from oxidative damage, supports detox, and reduces inflammation. People with high homocysteine or MTHFR gene variants often can’t recycle glutathione
If iron transfusions and pills aren’t working, the problem might be B vitamin deficiencies. Without enough B vitamins (like choline, biotin, or folate) or vitamin C, your body can’t absorb iron properly. Fixing these first can often restore
If iron transfusions and pills aren’t working, the problem might be B vitamin deficiencies. Without enough B vitamins (like choline, biotin, or folate) or vitamin C, your body can’t absorb iron properly. Fixing these first can often restore iron levels within a few months.
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What I see again and again is an inability to detox caused by failures in the Transsulfuration Pathway. This is your pathway that converts homocysteine to glutathione. If you have MTHFR or 16 other Gene SNPs, you will have problems with thi
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What I see again and again is an inability to detox caused by failures in the Transsulfuration Pathway. This is your pathway that converts homocysteine to glutathione. I
Many patients with POTS (Postural Orthostatic Tachycardia Syndrome) are told it’s “just bad luck,” but often it’s linked to key nutrient deficiencies. Low levels of B12, folate, copper, and glutathione can impair blood vessel and nervous sy
🧬 After 15+ years deep in genetics, Dr. Purser sees two root causes over and over again: 1️⃣ Inflammation 2️⃣ Gut & liver dysfunction. Almost every chronic issue—including fibromyalgia, fatigue, and brain fog—ties back to 17 homocysteine SN
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