Let’s explore “Folate, serum — lab reference”

Follow Dr. Purser’s discussion of folate metabolism and inflammation.

Everyone talks about MTHFR. But what if that is only one piece of the puzzle? MTHFR helps process folate, while MTR helps recycle homocysteine back into methionine with the help of vitamin B12. Two genes. Different roles. One interco

The older Purser genetics reference uses the heading “DAOA (AOC1)” in its gut section.

FOLR3 is the gene name for Folate Receptor 3. Learn what a specific result could mean and what to ask about it.

Explore rs2236225, rs1076991, folate-dependent one-carbon metabolism, nucleotide synthesis, homocysteine, and double homozygosity.

You eat something sweet. Your energy shoots up. Then suddenly you are exhausted, foggy, irritable, and reaching for something else to get you through the day. That cycle deserves a closer look. MTHFR variants can influence folate meta

What if the answers you've been searching for aren't found in another prescription—but inside your own cells? Most lab tests tell you what's circulating in your blood. But what if your cells are telling a different story? A Cellular Micro

What if everything you’ve been told about PCOS is missing the real culprit? Homocysteine isn’t just a random lab marker—it may be the hidden thread tying together hormone imbalance, inflammation, and the symptoms so many are struggling to m

PURSER WELLNESSFibromyalgia and Metallothionein DysfunctionsA conversation with Dr. Purser

Dr. Purser explains symptoms of Metallothionein dysfunctions and how metal toxicity can cause fibromyalgia. Learn how high serum copper levels cause painful inflammation in muscles, nerves, and joints. Explore the genetic components associated with fibromyalgia.

PURSER WELLNESSWhat is MTHFR? What can YOU do about it?A conversation with Dr. Purser

MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialized folates, B12 forms, and glutathione can bypass the blockages, and products like MTHFR Daily were designed specifically to fill these nutrient gaps so patients can restore energy and thrive.

PURSER WELLNESSWhat Happens If You Have A Gene SNP?A conversation with Dr. Purser

Genetic SNPs are tiny changes in your DNA that can drastically affect how well your enzymes and proteins work. For example, being homozygous for MTHFR C677T leaves that enzyme functioning at only about 30% efficiency, which can drain your energy and impair folate processing. Similarly, errors in SOD genes reduce your body’s ability to neutralize free radicals. While we can’t change your genes, we can work around them by identifying these weaknesses and filling the gaps with targeted nutrition and supplementation—helping your body function closer to its full potential.

PURSER WELLNESSGene Types ExplainedA conversation with Dr. Purser

Your genetic results might list “wild type,” “heterozygous,” or “homozygous,” but what does that mean? Wild type means both copies of your gene are normal, heterozygous means one is normal and one has a change, and homozygous means both copies have the same change. With genes like MTHFR, these variations can affect how efficiently your body processes nutrients like folate—sometimes cutting function by 40–70%—which is why targeted nutrition and testing matter.