IL4 encodes interleukin-4, a cytokine involved in Th2 immune responses and antibody class switching, including pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself.
Also calle…
MTHFS encodes an enzyme that converts 5-formyltetrahydrofolate into 5,10-methenyltetrahydrofolate. This places it in folate interconversion; it is not another name for MTHFR or a direct maker of methylfolate.
Also called:
Folinic acid has …
RAD50 encodes a DNA-repair protein. The surrounding genomic region also contains regulatory elements relevant to the nearby IL4, IL5 and IL13 cluster, so a locus association can concern more than the coding function of one gene.
Also called…
See how homocysteine connects to cysteine and glutathione. Follow seven simple steps, explore the side routes, and tap a word or building block to learn more.
Also called: Transsulfuration, Transsulphuration, Sulfur pathway, Cysteine synthe…
Ever remember something I said in a video but have no idea which video it was?
We’ve been working on that.
Introducing **Purser Wellness Explore** a new home for my teaching, organized so you can find the subjects that matter to you.
MTH…
Your local doctor will likely tell you that MTHFR testing and taking an MTHFR Daily supplement is a waste of money. They might even claim it isn't a real medical issue. After 15 years of hearing this pap, I can tell you they are flat-out wr…
Explore Toll-like receptor 4, lipopolysaccharide (LPS), HMGB1, innate immune sensing, and related inflammatory pathways.
Understand the connection
TLR4 helps recognize bacterial lipopolysaccharide, or LPS, with assistance from CD14 and MD-…
Years ago, I watched cystic fibrosis (CF) patients receive nebulized glutathione that didn’t seem to help.
Decades later, our team developed and patented the first fully functional, reduced, and stable form — VARS Glutathione.
Why does thi…
High homocysteine signals a broken transsulfuration pathway, leaving you unable to detox or convert it into glutathione. This shows up in conditions like PCOS and fibromyalgia, where patients often struggle with inflammation, pain, and even…
Discover the power of Glutathione! This super antioxidant acts like a spear for white blood cells, helping to detoxify by grabbing viruses, metals, and toxins from your system. Glutathione supports liver and kidney function, stabilizes infl…
Dr. Dan Purser here. I've been perturbed by the continuous flow of studies reporting the failure of antioxidants, particularly glutathione. Various research entities and pharmaceutical companies have attempted to exploit the power of antiox…
For quite some time now, I have been vexed by the constant stream of research papers that claim antioxidants have fallen short of expectations. Over the past half a decade or so, institutions such as Johns Hopkins, Mayo Clinic, and numerous…
Search looks for your words in titles, descriptions, available articles, learning guides, and video captions when available. The closest matches appear first. Duplicate posts are grouped, with links to other places you can read or watch them. Books, chapters, and reports have topic guides here; the original files and full book text are not available in this encyclopedia. Subscriber posts include a title and public summary; open Substack to read the full post.