Let’s explore “MTHFR, homocysteine, and immune signals”

A post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants, pain and wellbeing.

Genetic SNPs are tiny changes in your DNA that can drastically affect how well your enzymes and proteins work. For example, being homozygous for MTHFR C677T leaves that enzyme functioning at only about 30% efficiency, which can drain your e

😴 Feel like you took 3 Dramamine but all you had was a vitamin? You might be overmethylating—especially if you're taking too much MTHFR support like methylated B vitamins. If you’re drowsy, foggy, or exhausted, it’s time to back off, not pu

PURSER WELLNESSTired all the time? Are you Overmethylating?A conversation with Dr. Purser

😴 Feel like you took 3 Dramamine but all you had was a vitamin? You might be overmethylating—especially if you're taking too much MTHFR support like methylated B vitamins. If you’re drowsy, foggy, or exhausted, it’s time to back off, not push through. Try dropping to 1 capsule of MTHFR Daily and adjust slowly. Your body will thank you. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

🧬 After 15+ years deep in genetics, Dr. Purser sees two root causes over and over again: 1️⃣ Inflammation 2️⃣ Gut & liver dysfunction. Almost every chronic issue—including fibromyalgia, fatigue, and brain fog—ties back to 17 homocysteine SN

PURSER WELLNESSWhat are the ROOT CAUSES of you symptoms?A conversation with Dr. Purser

🧬 After 15+ years deep in genetics, Dr. Purser sees two root causes over and over again: 1️⃣ Inflammation 2️⃣ Gut & liver dysfunction. Almost every chronic issue—including fibromyalgia, fatigue, and brain fog—ties back to 17 homocysteine SNPs or PEMT mutations. That’s why he built treatment guides, books, and the CMA + Redox + genetic testing combo. If you’ve been told “everything looks normal” but still feel awful, this is where to look next. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants, gut and digestion.

PURSER WELLNESSThe Role of Glutathione in Reducing InflammationA conversation with Dr. Purser

VARS Glutathione works at the cellular level to calm inflammation by lowering cytokine activity. Cytokines are signaling molecules that, when overproduced, drive pain, fatigue, and chronic disease. By boosting your body’s master antioxidant—glutathione—VARS helps rebalance the immune system, reduce harmful cytokines, and protect your cells from oxidative stress. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.

Why do CMA tests matter so much? Because they check what’s going on inside your cells, not just your blood. 🧬 At Purser Wellness, we use CMA + genetic data (like MTHFR, PEMT, etc.) to spot the root of fatigue, inflammation, and more—then bu

If your transsulfuration pathway is off, it’s not just genetics—deficiencies in B6, glutathione, glycine, serine, glutamine, or methionine can block it too. 🧬 Without these, you can’t convert homocysteine to glutathione, leading to inflamma

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling.