THE PURSER WELLNESS ENCYCLOPEDIA

Let’s explore “Homocysteine and methylation”

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YouTubeAug 6, 2026

OVER-METHYLATION - Are Your B Vitamins Hurting You?

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Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

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InstagramMar 17, 2026

Struggling to feel better, even with a methylation support supplement? Here’s why it might not be working—and what…

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Struggling to feel better, even with a methylation support supplement? Here’s why it might not be working—and what you can do to finally see results.

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InstagramJun 11, 2025

Wondering how to get tested for MTHFR and other methylation gene issues? 🧬 The easiest way is with our The Works…

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Wondering how to get tested for MTHFR and other methylation gene issues? 🧬 The easiest way is with our The Works Genetic Test Kit—affordable, accurate, and designed to show how many SNPs you have. Results come fast, and we’ll help you inter

InstagramApr 11, 2025

MTHFR and methylation SNPs are closely related to the methionine and transsulfuration pathways. Everything in your…

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MTHFR and methylation SNPs are closely related to the methionine and transsulfuration pathways. Everything in your body is connected and trying to balance out. If you are tired, exhausted, or have unending anxiety, there’s a reason your bod

InstagramMar 8, 2025

What makes a good MTHFR methylation support product? You need to be careful in finding the right balance of…

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What makes a good MTHFR methylation support product? You need to be careful in finding the right balance of methylating vitamins and genetic hole fillers. Look at MTHFR Daily from Physician Designed for the best one in the world.

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