Let’s explore “fatigue”

PURSER WELLNESSWhat is Intracellular Testing?A conversation with Dr. Purser

Intracellular testing, or the CMA Cellular Micronutrient Assay, measures over 100 vitamins, minerals, amino acids, and antioxidants inside your cells—not just in your blood. Unlike serum tests, which show short-term levels, intracellular testing reveals what your cells have been missing over the last 100 days. Low levels can mean weak enzymes, non-functioning proteins, and accelerated aging. By identifying deficiencies and matching them with the correct nutrient forms for your genetics, you can target fatigue, anxiety, depression, and other chronic issues at the root. Get your CMA by calling o

Persistent pain, fatigue, and brain fog can arise from many conditions.

If you’ve been struggling with severe chronic fatigue, unexplained anxiety, or cardiovascular red flags, your genes might be trying to tell you something. Millions of patients walk out of traditional clinics with normal blood tests, only to be told their crippling symptoms are "all in their head." If you carry the C677T variant, you aren't crazy—you are dealing with a breakdown in cellular biochemistry. The Problem With Synthetic Folic Acid The standard advice from standard doctors is to take synthetic folic acid. For someone with the C677T genetic mutation, this is disastrous. Your enzyme pat

PURSER WELLNESSOVER-METHYLATION - Are Your B Vitamins Hurting You?A conversation with Dr. Purser

Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Feeling tired all the time is often dismissed as stress, aging, or a busy schedule. But persistent fatigue can have many possible causes, including nutritional issues that may not be obvious from routine testing. A Cellular Micronutrient

What if your recovery routine is just as important as your workout? Sore muscles, lingering fatigue, and slow recovery can make it harder to stay consistent in the gym. But what if supporting your body's recovery could help you get back

PURSER WELLNESSMTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving SweetsA conversation with Dr. Purser

MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.” In this video, we break down exactly why this happens: How MTHFR/methylation issues impair ATP (energy) production at the cellular level Why your body desperately reaches for quick glucose The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage The downstream effects on antioxidants, DNA repair, and overall energy How to finally break the cycle: Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests) Why our MTHFR Daily multivitamin was specifically formulated for this The power of CMA intracellular testing Intermittent fasting (12–16 hrs) Fasted cardio (even just a brisk walk) High-protein, real-food diet with minimal processed sugars If you’re tired of the sugar rollercoaster and want stable energy, this is for you. Links: Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious! #MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Why are so few people talking about copper when discussing fibromyalgia? Millions struggle with chronic pain, fatigue, brain fog, and countless unanswered questions. Yet one nutritional factor continues to fly under the radar for many pe

What if inflammation isn't the problem—it's the warning sign? Too many people are told to simply live with chronic inflammation, masking symptoms while the underlying triggers continue unchecked. Fatigue. Brain fog. Joint discomfort. Dige

PURSER WELLNESSFrom Bedridden to Thriving: Our Real Fibromyalgia JourneyA conversation with Dr. Purser

🎉 June Anniversary Special at Purser Wellness! Join Dr. Dan Purser MD’s team — Chantel (Chicky), Denise Purser, and Lois Schweigert from End Fibro with Natural Options — for an honest, heartfelt conversation about living well with fibromyalgia. We share real-life stories of flares, recovery, and ongoing improvement using Dr. Purser’s protocol. From severe teenage fibromyalgia to thriving as grandmothers, we discuss how the VARS Trio (Glutathione, SOD, and the game-changing Catalase) helps manage inflammation, cytokines, and hydrogen peroxide — plus practical tips on low-copper diet, serving sizes, gym recovery, weight loss, and consistency over perfection. Topics covered: • How to handle fibro flares quickly (catalase + SOD stories) • The importance of intracellular testing (CMA) & genetics • Low-copper eating guidelines & why serving size matters • Building strength and muscle after years of pain • Why we keep improving year after year 🔥 June Special: $100 off Genetic Testing + CMA (deepest discount of the year). One lucky order will be fully reimbursed! 👉 Order tests & supplements: https://danpursermd.com (or link in comments) If you or someone you love deals with fibromyalgia, chronic pain, fatigue, or inflammation, this episode is full of hope and actionable advice. 💬 Drop your biggest takeaway or question below — we read every comment! Timestamps: 00:00 - Intro & June Anniversary Sale 02:30 - Real flare story & catalase rescue 06:00 - Long-term improvement on the protocol 12:00 - Starting slow with supplements (topical tips) 23:00 - Low-copper diet & food list tips 36:00 - Gym recovery & building muscle 50:00 - Weight loss benefits & consistency #Fibromyalgia #ChronicPain #NaturalWellness #PurserWellness #FibroRecovery #LowCopperDiet Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

What if brain fog isn't a normal part of getting older? What if it's your body's way of telling you something is wrong? Too many people have accepted forgetfulness, poor focus, mental fatigue, and difficulty concentrating as part of every

What if too much copper — not too little — is the reason your body feels out of balance? For some people, excess copper may be linked to fatigue, mood changes, hormone issues, brain fog, and unexplained health struggles that never seem to