Hirschsprung’s disease & genetics
Explore enteric nerve development, aganglionosis, bowel function, RET, EDNRB, EDN3, SOX10, PHOX2B, and genetic syndromes discussed alongside Hirschsprung’s disease.
THE PURSER WELLNESS ENCYCLOPEDIA
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A RELATED COURSEYour MTHFR starting point
Explore the course 5 chapters, at your pace
New to this subject? Start with this free introduction.Crash Course on MTHFR & Genetic Terminology
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What’s searchable?IL-15 & homozygosity
Explore rs2857261, rs1057972, natural killer cells, CD8+ T cells, and questions about high-expression variants.
MAO-A & MAO-B: combined variants
Explore monoamine oxidase, the MAOA and MAOB genes, rs1137070, rs2072743, rs66323, rs1799836, rs2283729, neurotransmitter metabolism, dietary amines, and treatment research.
MTHFD1 & one-carbon metabolism
Explore rs2236225, rs1076991, folate-dependent one-carbon metabolism, nucleotide synthesis, homocysteine, and double homozygosity.
PAI-1 4G/5G & homocysteine
Explore SERPINE1 / PAI-1, rs1799889, 4G/5G, fibrinolysis, hyperhomocysteinemia (HHcy), vascular health, and differences between approaches to clotting risk.
TNF-alpha
Explore tumor necrosis factor-alpha, TNFR1, TNFR2, rs1800629, inflammatory signaling, and treatment comparisons in Purser Wellness teaching.
Tourette syndrome & tic disorders
Explore motor and vocal tics, brain circuits, dopamine, GABA, histamine pathways, behavioral therapies, and treatment and outlook.
A fast look at the genetic quirks I came across this week, from odd inherited traits to the ones that can seriously…
A fast look at the genetic quirks I came across this week, from odd inherited traits to the ones that can seriously affect health. Clear, curious, and a little alarming.
Homocysteine rarely gets the attention of cholesterol, blood sugar, or blood pressure.
Homocysteine rarely gets the attention of cholesterol, blood sugar, or blood pressure. It should. When homocysteine becomes elevated, it has been associated with cardiovascular disease, stroke, cognitive decline, blood clots, and other he
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Instagram listingWhat if your constant sugar cravings are not simply a willpower problem?
What if your constant sugar cravings are not simply a willpower problem? You wake up tired. You reach for sugar or quick carbohydrates. You feel better for a little while. Then the crash hits and you are searching for energy all over ag
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Instagram listingPAI-1 4G/5G Report – Homocysteine Complications and Brain Infarct Risk
Dr. Purser’s subscriber report on PAI-1 4G/5G, homocysteine, and brain infarct risk. Read the report on Substack.
Intracellular vs. Serum Nutrient Testing: Is More Data Actually Better?
Dan and Jackson discuss serum testing, intracellular nutrient results, REDOX, and the questions each kind of test addresses.
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