Let’s explore “Methylation, methionine, and transsulfuration: follow the connections”

A subscriber post from Purser Wellness on Substack, covering genetics and methylation, inflammation and antioxidants.

If your transsulfuration pathway is off, it’s not just genetics—deficiencies in B6, glutathione, glycine, serine, glutamine, or methionine can block it too. 🧬 Without these, you can’t convert homocysteine to glutathione, leading to inflamma

Homocysteine - a very difficult molecule to keep in balance if you have genetic errors that affect your methylation and transsulfuration pathway. What does that even mean? You aren’t processing glutathione correctly but you can mitigate its

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PURSER WELLNESSTMG A Viable Option For Homocysteine?A conversation with Dr. Purser

…'s got three methyl groups on it. Just a glycine that's had methylation groups added to it. But you might overmethylolate on that. Number one. Number two, it won't really lower your homocyine. If you have a genetically caused homoysteine le…

…der function. Several different conditions can produce it. Follow the pathway Dr. Purser discusses IL-6, Th17 signaling, B-cell activity, and related neuroinflammatory pathways. He also distinguishes direct inflammation from indirect kidne…

PURSER WELLNESSHow to Properly Treat Kids: Root Cause Medicine for Autism, ADHD, and Developmental ChallengesA conversation with Dr. Purser

…an't communicate. And the next thing I hear um at the 8week followup is, "How do we get him to shut up?" Because he's talking all the time. He talks in the back seat. He talks everywhere. Points out every sign. We didn't know he could read.…

PURSER WELLNESSMTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors Miss From the reading room

…(5-methyltetrahydrofolate). The downstream result? Impaired methylation, elevated plasma homocysteine, and a body-wide amplification of inflammatory cytokines. Homocysteine is not merely a cardiovascular marker. It is a potent “cytokine amp…

PURSER WELLNESSCope with Homocysteine Like a Pro!A conversation with Dr. Purser

…h. So, what's interesting, you were talking about PCOS, the connections to homoyine issues, transforation issues, as well as MTHFR and methylation issues. It's all interconnected. Homocyine SIS that cause hyperomocyura are strictly methylat…

PURSER WELLNESSAUTSIM - What is a potential ROOT CAUSE of Autism? Can it be helped?A conversation with Dr. Purser

…ve people to death to keep them off amino acids, especially methionine. And a wonderful physician in Colorado, a naturopath actually looked at all the data, all the study information, all the the collected data, and she concluded correctly …

…nd again is an inability to detox caused by failures in the Transsulfuration Pathway. This is your pathway that converts homocysteine to glutathione. If you have MTHFR or 16 other Gene SNPs, you will have problems with this pathway. In li…