Let’s explore “NF-kB”

…pathway Dr. Purser follows TLR2 signaling through MyD88 and NF-κB into cytokine production. This connects the initial recognition of a trigger with inflammation, blood-vessel and joint research, and the antioxidant network. Bring these que…

… connection between HMGB1, receptors such as RAGE and TLR4, NF-κB signaling, and ongoing tissue inflammation. He also discusses oxidative stress and the body’s antioxidant defenses. Bring these questions to your visit Ask which result is b…

…accharide (LPS), HMGB1, innate immune sensing, and related inflammatory pathways. Understand the connection TLR4 helps recognize bacterial lipopolysaccharide, or LPS, with assistance from CD14 and MD-2. It is part of the innate immune syst…

PURSER WELLNESSMTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors Miss From the reading room

…ding to elevated homocysteine that supercharges autoimmune inflammation . This is not fringe theory. It is the clinical reality I have mapped in my practice, refined over 12 years of data from thousands of patients, and will soon publish in…

PURSER WELLNESSDifficulty Sleeping? There’s More To It Than You Might ThinkFrom the reading room

…nic, and together we can move forward. Call or email us at info@danpursermd.com or 801-796-7667. Be well, Dr. P Dan Purser MD References Buysse DJ. Insomnia. JAMA. 2013;309(7):706-716. doi:10.1001/jama.2013.193 Cirelli C, Tononi G. The Slee…