NR3C1 encodes the glucocorticoid receptor, which helps tissues respond to cortisol and glucocorticoid medicines. Receptor genetics and measured cortisol levels answer different questions.
Also called: Nuclear Receptor Subfamily 3 Group C Me…
NR3C2 encodes the mineralocorticoid receptor, which responds to hormones such as aldosterone and helps regulate salt and fluid balance. It is distinct from the NR3C1 glucocorticoid receptor.
Also called: Mineralocorticoid Receptor / Nuclear…
NTRK2 encodes TrkB, a receptor involved in responding to neurotrophic signals such as BDNF. These signals support nervous-system function and plasticity. NTRK2 is not a phosphatidylserine absorption transporter.
Also called: Neurotrophic Re…
Makes an enzyme involved in producing phosphatidylcholine, a component of cell membranes. Genetic findings alone do not establish a choline deficiency.
Also called: Phosphatidylethanolamine N-Methyltransferase, choline, phosphatidylcholine
…
PON1 is discussed in relation to how the body handles some compounds and protects certain fats.
Also called: Paraoxonase 1
A different part of antioxidant handling
PON1 appears in Dr. Purser’s redox and conversion teaching alongside GST and…
PSEN1 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.
Also called:…
PSEN2 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.
Also called:…
PTGS2, commonly called COX-2, encodes an enzyme involved in prostaglandin production. Prostaglandins participate in pain, fever and inflammatory signaling.
Also called: COX2, Cyclooxygenase 2
COX-2 and inflammatory prostaglandins
PTGS2, com…
SERPINE1 makes PAI-1, a protein involved in breaking down blood clots. You may also see PAI4G used for this pathway.
Also called: PAI-1, PAI4G, Plasminogen Activator Inhibitor-1, Plasminogen Activator Inhibitor 1, 4G/5G Polymorphism
Balanci…
SHMT1 connects serine and glycine with folate chemistry.
Also called: Serine Hydroxymethyltransferase 1
Where amino acids meet folate
SHMT1 connects serine and glycine with folate pathways. That is one reason both nutrition and genetics can…
SOD1 helps convert superoxide inside cells as part of the body’s antioxidant defenses.
Also called: Superoxide Dismutase 1
Superoxide defense in its own setting
Dr. Purser teaches SOD as one member of an antioxidant team. SOD1 works primari…
SOD2 works in mitochondria as part of the body’s antioxidant defenses.
Also called: Superoxide Dismutase 2
Superoxide defense in its own setting
Dr. Purser teaches SOD as one member of an antioxidant team. SOD2 works in mitochondria and use…
Search looks for your words in titles, descriptions, available articles, learning guides, and video captions when available. The closest matches appear first. Duplicate posts are grouped, with links to other places you can read or watch them. Books, chapters, and reports have topic guides here; the original files and full book text are not available in this encyclopedia. Subscriber posts include a title and public summary; open Substack to read the full post.