Let’s explore “Methylation, methionine, and transsulfuration: follow the connections”

…utrient handling can all enter the same conversation. Those connections do not make an IBS label, Crohn’s disease or another diagnosis interchangeable, and a common variant is not a substitute for a digestive workup. A question to bring to …

…er Dr. Purser notes an indirect connection to homocysteine. Follow that connection through the wider folate network, including MTHFR, MTR and nutrient status, rather than interpreting GGH as a direct homocysteine reading. Some medicines als…

… two best-known MTHFR variants. Putting the pieces together Follow the connection to folate availability and the cellular processes that use one-carbon units. The pathway provides context, but it cannot tell you from the gene name alone whe…

…ahydrofolate Reductase, C677T, A1298C, folate, homocysteine Follow the pathway beyond MTHFR Dr. Purser teaches MTHFR within a larger folate and homocysteine pathway. MTHFR contributes to production of the folate form used in remethylation; …

…y alone. Putting the pieces together His wider map connects methylation with downstream sulfur handling and glutathione production. Learning the connection helps you distinguish raw materials, enzyme cofactors and current laboratory finding…

…l as consumed TCN2 appears in Dr. Purser’s homocysteine and methylation map because it concerns the transport of B12. The teaching distinction is between eating or supplementing a vitamin, transporting it, and using it in an enzyme reaction…

…ity goals affect options, and which measurements will guide follow-up? Reading your own results Bring your original report, current results, health history, and medicines to your visit. This information can help you ask questions, but it ca…

…places CETP in his cholesterol and cardiovascular teaching. Follow the connection through measured lipids, family history and overall cardiovascular risk. A SNP does not by itself select a CETP inhibitor or establish that HDL is low; medica…

…nking IL23A to IL23R and IL17A makes the sequence easier to follow: produce the cytokine, receive its signal and maintain a downstream inflammatory response. Genetic associations do not identify the correct immune treatment by themselves. A…

…ses interaction with homocysteine-related oxidative stress. Follow both parts of that model separately: evaluate the allergic pattern and measure the metabolic findings rather than assuming one proves the other. A question to bring to your …

…onversations connect. Now you have a place to explore those connections at your own pace. Search a topic. Watch a video. Read an article. Take a guided course. Look up a gene or an unfamiliar term without losing your place. You don’t need…

PURSER WELLNESSThe Master MTHFR Protocol Dr. Purser DesignedFrom the reading room

…eine, and Cytokines These physicians know almost zero about methylation or the FDA and HHS-approved intracellular micronutrient testing we use with our patients. (Yes, targeted vitamin deficiencies are often the hidden cause of the chronic …