THE PURSER WELLNESS ENCYCLOPEDIA

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Gene referenceSep 23, 2026

G6PC2

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G6PC2 encodes a glucose-6-phosphatase-related protein expressed in pancreatic islet cells. Common variation is associated with differences in fasting glucose regulation; it is not the insulin receptor.

Gene referenceSep 23, 2026

GGH

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GGH encodes gamma-glutamyl hydrolase, which removes glutamate residues from folate compounds. This affects folate handling and helps explain why folate metabolism includes retention and processing as well as intake.

Gene referenceSep 23, 2026

ALPL

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ALPL encodes tissue-nonspecific alkaline phosphatase, an enzyme important to bone and tooth mineralization and vitamin B6 metabolism. Persistently low alkaline phosphatase can deserve a different evaluation from a general nutrient deficiency.

Gene referenceSep 23, 2026

IL18

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IL18 encodes interleukin-18, a cytokine that can promote interferon-gamma responses in the appropriate immune context. Its receptor includes components encoded by IL18R1 and IL18RAP.

Health BlogSep 18, 2026

The Master MTHFR Protocol Dr. Purser Designed

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Your local doctor will likely tell you that MTHFR testing and taking an MTHFR Daily supplement is a waste of money. They might even claim it isn't a real medical issue. After 15 years of hearing this pap, I can tell you they are flat-out wrong . Every day that I run into abject medical ignorance—where medicine arrogantly refuses to bend to the hard truth of proven science—I remember Ignaz Semmelweis. Semmelweis died a broken pauper in an asylum, his life destroyed by the conventional doctors of his generation who refused to accept handwashing. Their dismissive attitude today stems not from mal

FacebookSep 15, 2026

Homocysteine rarely gets the attention of cholesterol, blood sugar, or blood pressure.

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Homocysteine rarely gets the attention of cholesterol, blood sugar, or blood pressure. It should. When homocysteine becomes elevated, it has been associated with cardiovascular disease, stroke, cognitive decline, blood clots, and other he

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