Let’s explore “Cytokine panel vocabulary”

PURSER WELLNESSThe Hidden Molecule Driving Inflammation: Understanding the Purser Model of HomocysteineFrom the reading room

…ts something more important is happening. The Real Problem: Cytokine Activation According to the Purser Model, homocysteine is not the primary cause of tissue damage. Instead, it acts as a marker of cytokine sensitivity . Cytokines are infl…

…tory process, rather than establishing the condition from a cytokine panel. Bring these questions to your visit Ask which antibody, imaging, and clinical findings support the diagnosis and how attacks will be prevented. New vision loss or …

…R5 is a receptor on cells, rather than a freely circulating cytokine. It receives the CXCL13 signal and helps direct B cells and follicular helper T cells. Follow the pathway Dr. Purser connects this navigation system with germinal centers…

…CD8+ T cells, and signaling in muscle and joint tissue. The cytokine IL-15 and its receptor IL15RA are related but different entries on a genetic or immune panel. Bring these questions to your visit Ask which result is being discussed: a g…

…ocessing → elevated homocysteine → massive inflammation and cytokine storms (IL-6, TNF-α, IL-17, etc.). High homocysteine (>10-12 µmol/L; ideal <7-8) acts like a "cytokine amplifier," driving Th17 skewing, oxidative stress, low glutathione…

PURSER WELLNESSMTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors Miss From the reading room

…homocysteine, and a body-wide amplification of inflammatory cytokines. Homocysteine is not merely a cardiovascular marker. It is a potent “cytokine amplifier.” When levels climb above 10–12 µmol/L (my functional optimum is <7–8 µmol/L), hom…

PURSER WELLNESSHow To Know If You Have High Homocysteine?A conversation with Dr. Purser

High homocysteine often shows up first as widespread inflammation—pain all over, poor circulation, or even early warning signs of cardiovascular problems like stroke and heart attack. The best way to know for sure is through testing: a blood test can measure homocysteine directly, while a CMA with Redox uncovers the vitamin deficiencies driving it. For genetic causes, the DRP Genetics panel screens 15–16 of the 17 known SNPs that can cause permanently high homocysteine. If your levels are fixed by genetics, reduced glutathione and targeted B vitamins (like MTHFR Daily) are key to balancing the

PURSER WELLNESSGlutathione and Your Ability To Detox?A conversation with Dr. Purser

Your body’s ability to detox depends on one critical pathway—turning homocysteine into glutathione. But for millions with MTHFR or other genetic SNPs, this process is broken, leaving them vulnerable to toxins, inflammation, and cytokine storms. That’s why VARS Glutathione is such a breakthrough: it’s reduced, functional, and proven to lower harmful cytokines like IL-8 and MCP-1, giving your body the detox power it needs. After 15 years of research and real patient results, it’s the only oral glutathione that actually works where it matters—inside your cells.

Most doctors run standard serum blood tests, see a "normal" nutrient level, and send you home. But measuring floating nutrients in your liquid serum is like looking at the paint on a house to see if the plumbing works inside. After reviewing over 40,000 advanced intracellular vitamin lab panels, the truth is clear: intracellular glutathione vs serum levels tell two entirely different stories. Your serum can look completely fine while your cells are completely depleted of the master antioxidant needed to protect your life. The Cytokine Threat When methylation breaks down and homocysteine elevat

Explore the cytokine pathways discussed alongside dryness and systemic symptoms.

Explore the eye inflammation and cytokine connections in Dr. Purser’s report.

CD14 helps immune cells recognize microbial components, including bacterial lipopolysaccharide, as part of innate immune signaling. This places it upstream of some cytokine responses.