THE PURSER WELLNESS ENCYCLOPEDIA

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Gene referenceSep 23, 2026

MAOB

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…B encodes monoamine oxidase B, an enzyme involved in breaking down monoamine compounds, including dopamine. It does not simply build dopamine, and a DNA marker is not a neurotransmitter measurement. Also called: MAO-B, Monoamine Oxidase B B…

Gene referenceSep 23, 2026

MMP3

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…es matrix metalloproteinase 3, an enzyme involved in breaking down components of the extracellular matrix. Controlled remodeling is part of repair, while excess activity can accompany inflammatory tissue damage. Also called: Matrix Metallop…

Gene referenceSep 23, 2026

MTHFD1

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… in the body. Also called: Methylenetetrahydrofolate Dehydrogenase 1 Folate has several working forms Dr. Purser includes MTHFD1 among genes involved in folate interconversion. The lesson is that folate participates in several reactions and…

Gene referenceSep 23, 2026

MTHFD1L

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…steine chapters include MTHFD1L in the wider folate-related genetic map. Also called: Methylenetetrahydrofolate Dehydrogenase 1-Like A mitochondrial contribution to one-carbon metabolism The homocysteine chapters include MTHFD1L in the wide…

Gene referenceSep 23, 2026

MTHFR

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…me that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency. Also called: Methylenetetrahydrofolate Reductase, C677T, A1298C, folate, hom…

Gene referenceSep 23, 2026

MTR

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Makes the methionine synthase enzyme, which uses vitamin B12 in the conversion of homocysteine to methionine. Also called: Methionine Synthase The B12-dependent step In Dr. Purser’s teaching map, MTR is the B12-dependent step that converts …

Gene referenceSep 23, 2026

MTRR

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…elps maintain the activity of methionine synthase, connecting B12-related chemistry with homocysteine metabolism. Also called: Methionine Synthase Reductase Keeping the remethylation system working Dr. Purser teaches MTRR alongside MTR beca…

Gene referenceSep 23, 2026

NOS3

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…ndothelial nitric oxide synthase, which helps blood vessels generate nitric oxide, a signal involved in vascular relaxation. This pathway is distinct from a blood pressure measurement or a diagnosis of vascular disease. Also called: Nitric …

Gene referenceSep 23, 2026

NQO1

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NQO1 is the gene name for NAD(P)H Quinone Oxidoreductase 1. Learn what a specific result could mean and what to ask about it. Also called: NAD(P)H Quinone Oxidoreductase 1 Quinone handling within the redox network Dr. Purser includes NQO1 i…

Gene referenceSep 23, 2026

NR3C1

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NR3C1 encodes the glucocorticoid receptor, which helps tissues respond to cortisol and glucocorticoid medicines. Receptor genetics and measured cortisol levels answer different questions. Also called: Nuclear Receptor Subfamily 3 Group C Me…

Gene referenceSep 23, 2026

PEMT

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Makes an enzyme involved in producing phosphatidylcholine, a component of cell membranes. Genetic findings alone do not establish a choline deficiency. Also called: Phosphatidylethanolamine N-Methyltransferase, choline, phosphatidylcholine …

Gene referenceSep 23, 2026

PON1

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…alled: Paraoxonase 1 A different part of antioxidant handling PON1 appears in Dr. Purser’s redox and conversion teaching alongside GST and NQO1. The genetics reference discusses it in relation to handling particular compounds and protecting…

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