…B encodes monoamine oxidase B, an enzyme involved in breaking down monoamine compounds, including dopamine. It does not simply build dopamine, and a DNA marker is not a neurotransmitter measurement.
Also called: MAO-B, Monoamine Oxidase B
B…
…es matrix metalloproteinase 3, an enzyme involved in breaking down components of the extracellular matrix. Controlled remodeling is part of repair, while excess activity can accompany inflammatory tissue damage.
Also called: Matrix Metallop…
… in the body.
Also called: Methylenetetrahydrofolate Dehydrogenase 1
Folate has several working forms
Dr. Purser includes MTHFD1 among genes involved in folate interconversion. The lesson is that folate participates in several reactions and…
…steine chapters include MTHFD1L in the wider folate-related genetic map.
Also called: Methylenetetrahydrofolate Dehydrogenase 1-Like
A mitochondrial contribution to one-carbon metabolism
The homocysteine chapters include MTHFD1L in the wide…
…me that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.
Also called: Methylenetetrahydrofolate Reductase, C677T, A1298C, folate, hom…
Makes the methionine synthase enzyme, which uses vitamin B12 in the conversion of homocysteine to methionine.
Also called: Methionine Synthase
The B12-dependent step
In Dr. Purser’s teaching map, MTR is the B12-dependent step that converts …
…elps maintain the activity of methionine synthase, connecting B12-related chemistry with homocysteine metabolism.
Also called: Methionine Synthase Reductase
Keeping the remethylation system working
Dr. Purser teaches MTRR alongside MTR beca…
…ndothelial nitric oxide synthase, which helps blood vessels generate nitric oxide, a signal involved in vascular relaxation. This pathway is distinct from a blood pressure measurement or a diagnosis of vascular disease.
Also called: Nitric …
NQO1 is the gene name for NAD(P)H Quinone Oxidoreductase 1. Learn what a specific result could mean and what to ask about it.
Also called: NAD(P)H Quinone Oxidoreductase 1
Quinone handling within the redox network
Dr. Purser includes NQO1 i…
NR3C1 encodes the glucocorticoid receptor, which helps tissues respond to cortisol and glucocorticoid medicines. Receptor genetics and measured cortisol levels answer different questions.
Also called: Nuclear Receptor Subfamily 3 Group C Me…
Makes an enzyme involved in producing phosphatidylcholine, a component of cell membranes. Genetic findings alone do not establish a choline deficiency.
Also called: Phosphatidylethanolamine N-Methyltransferase, choline, phosphatidylcholine
…
…alled: Paraoxonase 1
A different part of antioxidant handling
PON1 appears in Dr. Purser’s redox and conversion teaching alongside GST and NQO1. The genetics reference discusses it in relation to handling particular compounds and protecting…
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