…f immune cells, including natural killer cells and memory CD8 T cells. Its receptor system includes IL15RA.
Also called:
Supporting immune-cell survival
IL15 encodes a cytokine involved in the survival and activity of immune cells, includi…
…makes IL-15 signaling relevant?
Variant IDs in the teaching reference: rs2228059
Where the VARS Triad and MTHFR Daily fit
If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and the VARS Triad: VARS Glutathion…
… established clinical picture beyond a general inflammation label?
Variant IDs in the teaching reference: rs11556218, rs4072111, rs4778889
Also called: IL-16, Interleukin 16
Where the VARS Triad and MTHFR Daily fit
If you are exploring homo…
…he Th17 pathway, which is supported by signals including IL-23.
Also called:
Th17 signaling and persistent inflammation
IL17A encodes interleukin-17A, a cytokine involved in defense at tissue barriers and inflammatory signaling. It belongs…
IL18 encodes interleukin-18, a cytokine that can promote interferon-gamma responses in the appropriate immune context. Its receptor includes components encoded by IL18R1 and IL18RAP.
Also called:
An inflammatory signal that connects to int…
IL18R1 encodes a component of the receptor for IL-18. It works with an accessory component, IL18RAP, to support IL-18 signaling.
Also called:
The binding side of the IL-18 receptor
IL18R1 encodes a component of the receptor for IL-18. It w…
IL18RAP encodes an accessory protein in the IL-18 receptor complex. The receptor needs coordinated components to translate an extracellular signal into a cellular response.
Also called:
The accessory component of IL-18 signaling
IL18RAP en…
…ing done to identify its cause?
Variant IDs in the teaching reference: rs1143634, rs16944
Also called: IL-1B, Interleukin 1B
Where the VARS Triad and MTHFR Daily fit
If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTH…
IL22 encodes a cytokine that acts on tissues such as epithelial barriers. It can support barrier defense and repair, while its effects depend on the tissue and inflammatory setting.
Also called:
Barrier defense, repair and excess tissue gr…
IL23A encodes the p19 subunit of interleukin-23. Together with the p40 subunit encoded by IL12B, it forms a cytokine involved in supporting Th17 responses.
Also called:
The p19 component of IL-23
IL23A encodes the p19 subunit of interleuki…
IL2RA encodes the alpha chain of the interleukin-2 receptor, also called CD25. It is involved in immune activation and regulatory T-cell biology; a soluble receptor measurement is distinct from a DNA result.
Also called:
CD25 and immune-ce…
IL4 encodes interleukin-4, a cytokine involved in Th2 immune responses and antibody class switching, including pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself.
Also calle…
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