THE PURSER WELLNESS ENCYCLOPEDIA

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Gene referenceSep 23, 2026

FOLR1

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FOLR1 encodes folate receptor alpha, which helps cells take up folate and has an important role in folate transport at the brain’s barriers. Blood folate and folate availability in the nervous system are not identical measurements.

Gene referenceSep 23, 2026

GSTO1

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GSTO1 belongs to the omega family of glutathione S-transferases. These enzymes participate in redox chemistry, with roles that differ from the better-known GSTM1 and GSTP1 pathways.

Gene referenceSep 23, 2026

PSEN1

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PSEN1 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.

Gene referenceSep 23, 2026

PSEN2

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PSEN2 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.

Gene referenceSep 23, 2026

CCL2

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CCL2 encodes MCP-1, a chemokine that attracts monocytes toward sites of immune activity. Recruitment is a different task from the cytokines that activate those cells once they arrive.

Gene referenceSep 23, 2026

GSTO2

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GSTO2 encodes glutathione S-transferase omega 2, a redox enzyme with dehydroascorbate reductase activity that connects glutathione chemistry with vitamin C recycling. It is a separate gene from GSTO1.

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