THE PURSER WELLNESS ENCYCLOPEDIA

Let’s explore “Primary ovarian insufficiency and immune signals”

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Gene referenceSep 23, 2026

CD14

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CD14 helps immune cells recognize microbial components, including bacterial lipopolysaccharide, as part of innate immune signaling. This places it upstream of some cytokine responses.

Gene referenceSep 23, 2026

IL6

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IL6 encodes interleukin-6, a cytokine involved in immune responses and acute-phase signaling. It can appear in discussions of infection, chronic inflammation and metabolic health, with effects that depend on the context.

Gene referenceSep 23, 2026

TNF

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TNF encodes tumor necrosis factor, an immune-signaling protein involved in inflammation, host defense and regulation of cell survival. Its name should not be read as proof that a TNF result indicates cancer.

Gene referenceSep 23, 2026

CCL3

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CCL3 encodes MIP-1 alpha, a chemokine involved in attracting and activating immune cells. It is related to CCL4, or MIP-1 beta, but the two genes and proteins are distinct.

Gene referenceSep 23, 2026

CCL4

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CCL4 encodes MIP-1 beta, a chemokine involved in attracting immune cells. It participates in a recruitment network that includes CCL2, CXCL8 and related chemokines.

Gene referenceSep 23, 2026

CCL5

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CCL5, also called RANTES, is a chemokine that helps direct immune-cell movement. Chemokines tell cells where to go, which is different from measuring the total strength of an immune response.

Gene referenceSep 23, 2026

IL16

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IL16 encodes interleukin-16, a cytokine involved in attracting and influencing immune cells, including CD4-expressing cells. Its recruitment role helps separate it from other numbered interleukins.

Gene referenceSep 23, 2026

IL17A

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…ling. It belongs to the Th17 pathway, which is supported by signals including IL-23. Also called: Th17 signaling and persistent inflammation IL17A encodes interleukin-17A, a cytokine involved in defense at tissue barriers and inflammatory …

Gene referenceSep 23, 2026

TGFB1

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TGFB1 encodes transforming growth factor beta 1, which has roles in immune regulation, tissue repair and extracellular-matrix production. Its effects can include both regulation of inflammation and promotion of fibrosis.

Report teachingAug 16, 2026

TLR2

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Explore Toll-like receptor 2, microbial and damage signals, TLR1, TLR6, and MyD88 signaling. Understand the connection TLR2 is a pattern-recognition receptor that helps immune cells detect components of microbes and damaged tissue. It ofte…

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