THE PURSER WELLNESS ENCYCLOPEDIA

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Gene referenceSep 23, 2026

FOLR1

FOLR1 encodes folate receptor alpha, which helps cells take up folate and has an important role in folate transport at the brain’s barriers. Blood folate and folate availability in the nervous system are not identical measurements.

Gene referenceSep 23, 2026

FOLR2

FOLR2 encodes folate receptor beta, a folate-binding protein expressed in particular cell types, including subsets of immune cells. It is distinct from the FOLR1 receptor and the SLC19A1 reduced folate carrier.

Gene referenceSep 23, 2026

FTO

FTO is studied in relation to body weight and energy balance. Common variants can contribute to population-level differences in obesity susceptibility, alongside many other genes and environmental factors.

Gene referenceSep 23, 2026

G6PC2

G6PC2 encodes a glucose-6-phosphatase-related protein expressed in pancreatic islet cells. Common variation is associated with differences in fasting glucose regulation; it is not the insulin receptor.

Gene referenceSep 23, 2026

GDF5

GDF5 encodes growth differentiation factor 5, a signaling protein involved in skeletal development, joint formation and cartilage biology. Its name does not mean a SNP measures the ability to build muscle.

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