THE PURSER WELLNESS ENCYCLOPEDIA
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What’s searchable?IL33 encodes interleukin-33, a signal that can act as an alarmin during tissue stress and promote type 2 immune responses. It belongs in a different functional group from chemokines that recruit cells. Also called: An alarmin in allergic s…
IL5 encodes interleukin-5, a cytokine important to eosinophil growth, survival and activation. Eosinophils are involved in selected allergic and other inflammatory conditions. Also called: An eosinophil-focused cytokine IL5 encodes interle…
IL6R encodes the interleukin-6 receptor. Membrane-bound and soluble receptor pathways help explain why IL-6 biology involves more than the amount of cytokine in a single blood sample. Also called: Receiving and relaying the IL-6 signal IL6…
MTHFS encodes an enzyme that converts 5-formyltetrahydrofolate into 5,10-methenyltetrahydrofolate. This places it in folate interconversion; it is not another name for MTHFR or a direct maker of methylfolate. Also called: Folinic acid has …
RAD50 encodes a DNA-repair protein. The surrounding genomic region also contains regulatory elements relevant to the nearby IL4, IL5 and IL13 cluster, so a locus association can concern more than the coding function of one gene. Also called…
TGFB1 encodes transforming growth factor beta 1, which has roles in immune regulation, tissue repair and extracellular-matrix production. Its effects can include both regulation of inflammation and promotion of fibrosis. Also called: Repai…
TNFRSF10A encodes death receptor 4, or DR4, a receptor that can receive the TRAIL signal and participate in regulated cell-death pathways. TRAIL itself is encoded by TNFSF10. Also called: DR4 receives the TRAIL signal TNFRSF10A encodes dea…
TNFSF10 encodes TRAIL, a signaling protein involved in regulated cell death through particular receptors. It is a different member of the TNF-related signaling family from TNF itself. Also called: TRAIL and regulated cell death TNFSF10 enc…
Your local doctor will likely tell you that MTHFR testing and taking an MTHFR Daily supplement is a waste of money. They might even claim it isn't a real medical issue. After 15 years of hearing this pap, I can tell you they are flat-out wr…
GABPA is a gene involved in controlling how other genes are used. You may see the label GABP1 in older materials; check the exact variant on your own report. Also called: GABP1, GA Binding Protein Transcription Factor Subunit Alpha Start he…
Explore multiple sclerosis (MS), central nervous system inflammation, myelin, symptoms, and related immune signals. Understand the connection Multiple sclerosis involves immune-mediated injury to myelin and other nervous-system structures.…
Homocysteine rarely gets the attention of cholesterol, blood sugar, or blood pressure. It should. When homocysteine becomes elevated, it has been associated with cardiovascular disease, stroke, cognitive decline, blood clots, and other he…
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