F9 encodes coagulation factor IX. Disease-causing variants can result in hemophilia B, an inherited bleeding disorder, but a panel marker is not equivalent to a confirmed disease-causing finding.
Also called:
Factor IX and the bleeding sid…
IL16 encodes interleukin-16, a cytokine involved in attracting and influencing immune cells, including CD4-expressing cells. Its recruitment role helps separate it from other numbered interleukins.
Also called:
A cytokine involved in immun…
IL18 encodes interleukin-18, a cytokine that can promote interferon-gamma responses in the appropriate immune context. Its receptor includes components encoded by IL18R1 and IL18RAP.
Also called:
An inflammatory signal that connects to int…
IL4 encodes interleukin-4, a cytokine involved in Th2 immune responses and antibody class switching, including pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself.
Also calle…
MTHFS encodes an enzyme that converts 5-formyltetrahydrofolate into 5,10-methenyltetrahydrofolate. This places it in folate interconversion; it is not another name for MTHFR or a direct maker of methylfolate.
Also called:
Folinic acid has …
RAD50 encodes a DNA-repair protein. The surrounding genomic region also contains regulatory elements relevant to the nearby IL4, IL5 and IL13 cluster, so a locus association can concern more than the coding function of one gene.
Also called…
See how homocysteine connects to cysteine and glutathione. Follow seven simple steps, explore the side routes, and tap a word or building block to learn more.
Also called: Transsulfuration, Transsulphuration, Sulfur pathway, Cysteine synthe…
MTHFR gene variants can affect how your body processes folate and methylation, key factors in overall health.
While they don’t directly cause blood sugar crashes, understanding your genetics, nutrition, sleep, stress, and nutrient status c…
Ever remember something I said in a video but have no idea which video it was?
We’ve been working on that.
Introducing **Purser Wellness Explore** a new home for my teaching, organized so you can find the subjects that matter to you.
MTH…
Your local doctor will likely tell you that MTHFR testing and taking an MTHFR Daily supplement is a waste of money. They might even claim it isn't a real medical issue. After 15 years of hearing this pap, I can tell you they are flat-out wr…
Explore multiple sclerosis (MS), central nervous system inflammation, myelin, symptoms, and related immune signals.
Understand the connection
Multiple sclerosis involves immune-mediated injury to myelin and other nervous-system structures.…
What if the place you call home is also the place making you question your health?
A family.
A farmhouse.
Unexplained symptoms.
And a hidden problem they never expected.
Black mold.
Mold exposure can become a serious concern in dam…
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