IL17A
In the reference guideIL17A encodes interleukin-17A, a cytokine involved in defense at tissue barriers and inflammatory signaling. It belongs to the Th17 pathway, which is supported by signals including IL-23.
THE PURSER WELLNESS ENCYCLOPEDIA
Let’s explore “IL-17A rs2275913”
5 resources for your curiosity
What’s searchable?IL-17A rs2275913
In the titleExplore Th17 cells, mucosal immunity, the rs2275913 promoter variant, and inflammatory conditions.
Psoriasis and cytokine pathways
Some search terms matchedFollow the IL-23 and IL-17 conversation in Dr. Purser’s psoriasis report.
IL23R
Some search terms matchedIL23R encodes part of the receptor that receives IL-23 signals. This connects the gene to the maintenance of Th17-related immune responses, which differ from the Th2 patterns discussed in allergy.
IL23A
Some search terms matched… and psoriasis-related teaching. Linking IL23A to IL23R and IL17A makes the sequence easier to follow: produce the cytokine, receive its signal and maintain a downstream inflammatory response. Genetic associations do not identify the correc…
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