Let’s explore “IL-23R”

IL23R encodes part of the receptor that receives IL-23 signals. This connects the gene to the maintenance of Th17-related immune responses, which differ from the Th2 patterns discussed in allergy.

Explore NAFLD, NASH, MASLD, MASH, hepatitis, the IL-23/IL-17 axis, and liver inflammation.

Explore interleukin-23 receptor, JAK2, TYK2, STAT3, and related immune signaling.

Explore the p19 and p40 subunits, interleukin-23, and the difference between the IL23A gene and the IL23R receptor.

PURSER WELLNESSVARS TRIAD | What Does That Mean? | Live with Dan Purser MDA conversation with Dr. Purser

Discover the power of the VARS Triad (also called the REDOX Triad)—Dr. Dan Purser MD’s groundbreaking, patented antioxidant protocol featuring VARS Glutathione, VARS SOD, and VARS Catalase. In this live session, Dr. Purser breaks down what VARS stands for (Validated, Absorbable, Reduced, Stable), how this physician-designed trio supports your body’s natural redox balance, quiets inflammation and cytokines at the root-cause level, and helps overcome genetic challenges like high homocysteine, oxidative stress, and related chronic issues. Perfect for anyone exploring advanced functional medicine and targeted supplementation. Learn more at https://physiciandesigned.com/blogs/glutathione/discover-the-vars-trio-your-bodys-ultimate-antioxidant-powerhouse

PURSER WELLNESSAutism Answered - Root Cause Solved with #1 Reviewed MD in the USAA conversation with Dr. Purser

…her kind of some kind of other severe cytoine disorder like IL23R or IL6 or dilate. Um u that's back to the homocyine problem. You treat that with glutathione too because it lowers the cytoines that not my claim. There's tons of research on…

PURSER WELLNESSHow to Properly Treat Kids: Root Cause Medicine for Autism, ADHD, and Developmental ChallengesA conversation with Dr. Purser

…er IL23 and IL17? This person has a double variant in their IL23R. Yeah, 23R. I deal with about four or five of those cases a week. some really prominent people. You'd be surprised. Um um they found out I was the number one ranked MD in the…

…g the pieces together The teaching links the gut story with IL23R, PEMT and folate-related pathways: immune signaling, membranes/bile and nutrient handling can all enter the same conversation. Those connections do not make an IBS label, Cro…

…g the pieces together The teaching links the gut story with IL23R, PEMT and folate-related pathways: immune signaling, membranes/bile and nutrient handling can all enter the same conversation. Those connections do not make an IBS label, Cro…

…tings, including his sickle-cell teaching. IL17A, IL23A and IL23R represent different parts of the same network: a downstream signal, an upstream cytokine component and a receptor. Their variants do not diagnose an inflammatory disease or s…

…in colitis and psoriasis-related teaching. Linking IL23A to IL23R and IL17A makes the sequence easier to follow: produce the cytokine, receive its signal and maintain a downstream inflammatory response. Genetic associations do not identify …

PURSER WELLNESSThe Hidden Molecule Driving Inflammation: Understanding the Purser Model of HomocysteineFrom the reading room

Most people have never heard of homocysteine , yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model , which explains why ho