Let’s explore “Blood-vessel health: genetics, metabolism, and measured risk”

Explore Dr. Purser’s connection between methylation and purine pathways.

…o called: Apolipoprotein E Lipid transport and brain-health risk APOE encodes a protein that carries lipids between cells. The familiar APOE e2, e3 and e4 groupings depend on the combination of rs429358 and rs7412, not on either marker read…

…with his homocysteine and redox framework. IL6 variation, a measured IL-6 concentration and a diagnosis of inflammatory disease are three different kinds of information. IL6R adds the receptor side of the story. More from the teaching: Infl…

NAT2 encodes N-acetyltransferase 2, which helps process certain drugs and other compounds. Combinations of variants can influence acetylation status; one SNP usually does not tell the entire story.

…hing connections should be distinguished from what a single blood measurement proves. Review current nutrient status, clinical context and changes over time; do not assume that a common SNP means homocysteine cannot change. Lowering a marke…

CETP transfers cholesteryl esters between lipoprotein particles. This helps explain why the balance of HDL and other lipid particles is more complex than a single cholesterol number.

…ful bridge from redox and homocysteine teaching to NOS3 and vessel function. The genotype does not measure ADMA concentration, kidney function or vascular damage. A question to bring to your visit What do my kidney function, blood pressure …

IL18 encodes interleukin-18, a cytokine that can promote interferon-gamma responses in the appropriate immune context. Its receptor includes components encoded by IL18R1 and IL18RAP.

…nd antioxidant support. He looks at gene findings alongside blood tests, nutrient results, symptoms, medicines and how a person responds. There are several questions to consider: Is cysteine available? Can the cells make glutathione? How i…

C3 is the gene name for Complement C3. Learn what a specific result could mean and what to ask about it.

CCR3 is the gene name for C-C Motif Chemokine Receptor 3. Learn what a specific result could mean and what to ask about it.

Encodes cubilin, part of a receptor system involved in uptake of the intrinsic-factor–B12 complex.