Let’s explore “Blood/hemoglobin, urine — lab reference”

LAB CLASS SIGN UP. Like I said these will be gone by tonight at close. Jump on it now if you want a cheap way to become my patient plus learn a TON. Plus a WDW CUPCAKE (yes, a ZEBRA DOME) to the top question that night of the class -- I wi

JANUARY ON LINE LAB CLASS -- the one I announced last night for January 7th. Still pondering how to put that together. We will move quickly when we decide because we need to help you get labs (some nut not all). And you need to get us cop

PURSER WELLNESSGENOVA™ Neopterin Biopterin Urine Profile for MTHFRFrom the reading room

This test result is bad and could indicate an infection, especially viral. This is a great test for those with A1298C and especially who are Homozygous A1298C. Neopterin is bad while biopterin is good. If neopterin is repeatedly high, the BH4 is low. Neopterin is a sensitive marker of cellular mediated immunity. Reduced levels reflect cellular immunity weakening. Increased neopterin occur with infectious, inflammatory, immune system dysfunction or neoplastic disease evolution. Excessive neopterin negatively impacts the Nitric Oxide pathway in the body (e.g. excessive peroxynitrite formation an

PURSER WELLNESSHomocysteine is the Secret AssasinA conversation with Dr. Purser

Homocysteine is nasty — but here’s the truth no one tells you. It doesn’t kill you directly — it triggers white blood cells to release IL-8 and MCP-1, causing inflammation, kidney failure, heart attacks, and strokes. Most doctors don’t even check it anymore, thinking there’s no fix. But there is. Whether from 17 genetic SNPs or 12 vitamin deficiencies (like B6 or B12), you can address it by supporting your body’s ability to convert homocysteine into glutathione.

PURSER WELLNESSCopper Overload In Body - What Can You Do?A conversation with Dr. Purser

Copper is essential for life—it helps enzymes work, supports SOD1 for antioxidant defense, and even prepares iron to carry oxygen in the blood. But when copper builds up in the bloodstream instead of entering cells, it causes pain, tender points, and migraines. This often ties back to genes like CBS, NAT2, and glutathione-related SNPs that impair copper transport. The solution is supporting ceruloplasmin—the copper-binding protein—with targeted nutrients like B6, zinc, and NAC. That’s why Copper Balance was created: to move copper where it belongs and help symptoms finally improve. Visit PhysicianDesigned.com or Amazon for Copper Balance. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSThe Hidden Molecule Driving Inflammation: Understanding the Purser Model of HomocysteineFrom the reading room

Most people have never heard of homocysteine , yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model , which explains why ho

ESR1 encodes estrogen receptor alpha, which helps cells respond to estrogen. Receptor signaling is different from the amount of estrogen measured in blood.

FOLR1 encodes folate receptor alpha, which helps cells take up folate and has an important role in folate transport at the brain’s barriers. Blood folate and folate availability in the nervous system are not identical measurements.

KIT encodes a receptor tyrosine kinase that responds to stem cell factor. It participates in blood-cell development and mast-cell biology, making the exact variant and testing context especially important.

NOS3 encodes endothelial nitric oxide synthase, which helps blood vessels generate nitric oxide, a signal involved in vascular relaxation. This pathway is distinct from a blood pressure measurement or a diagnosis of vascular disease.

SERPINE1 makes PAI-1, a protein involved in breaking down blood clots. You may also see PAI4G used for this pathway.

VDR encodes the vitamin D receptor, which helps regulate gene activity in response to active vitamin D. A receptor variant does not by itself mean receptors are absent or that the blood vitamin D level is low.