ESR1 encodes estrogen receptor alpha, which helps cells respond to estrogen. Receptor signaling is different from the amount of estrogen measured in blood.
Also called: Estrogen Receptor 1
Estrogen signaling depends on the receptor
ESR1 enc…
Encodes an enzyme involved in fatty-acid metabolism.
Also called: Fatty Acid Desaturase 1 / D5D
The form of a fatty acid matters
Dr. Purser teaches FADS genes as a conversion pathway. FADS1 participates in a delta-5 desaturase step in fatty…
FOLH1 helps break down folate from food so it can be absorbed. This is different from the MTHFR step.
Also called: Folate Hydrolase 1
Folate handling begins before remethylation
Dr. Purser’s genetic chapters include FOLH1 in folate handling…
FOLR1 encodes folate receptor alpha, which helps cells take up folate and has an important role in folate transport at the brain’s barriers. Blood folate and folate availability in the nervous system are not identical measurements.
Also cal…
GAD1 helps your body make GABA, a chemical messenger, from glutamate.
Also called: Glutamate Decarboxylase 1
The glutamate-to-GABA connection
Dr. Purser’s course uses GAD/GABA teaching to explain a connection between excitatory and inhibito…
GPX1 helps cells use glutathione to handle peroxides.
Also called: Glutathione Peroxidase 1
Glutathione has enzyme partners
Dr. Purser teaches the glutathione peroxidase family alongside selenium and antioxidant support. GPX1 helps illustra…
GSTM1 helps your body use glutathione to process some compounds.
Also called: Glutathione S-Transferase Mu 1
Using glutathione in conjugation
GSTM1 belongs to the glutathione transferase family. These enzymes use glutathione in conjugation …
GSTO1 belongs to the omega family of glutathione S-transferases. These enzymes participate in redox chemistry, with roles that differ from the better-known GSTM1 and GSTP1 pathways.
Also called: Glutathione S-Transferase Omega 1
An omega-fa…
GSTP1 helps your body use glutathione to process some compounds.
Also called: Glutathione S-Transferase Pi 1
Using glutathione in conjugation
GSTP1 belongs to the glutathione transferase family. These enzymes use glutathione in conjugation …
GSTT1 helps your body use glutathione to process some compounds.
Also called: Glutathione S-Transferase Theta 1, GSTT
Using glutathione in conjugation
GSTT1 belongs to the glutathione transferase family. These enzymes use glutathione in con…
MTHFD1 helps move folate between forms used for different jobs in the body.
Also called: Methylenetetrahydrofolate Dehydrogenase 1
Folate has several working forms
Dr. Purser includes MTHFD1 among genes involved in folate interconversion. T…
The homocysteine chapters include MTHFD1L in the wider folate-related genetic map.
Also called: Methylenetetrahydrofolate Dehydrogenase 1-Like
A mitochondrial contribution to one-carbon metabolism
The homocysteine chapters include MTHFD1L i…
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