THE PURSER WELLNESS ENCYCLOPEDIA

Let’s explore “Homocysteine and methylation”

Explore this topic as a step-by-step interactive map.MTHFR, the citric acid cycle & ATP
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InstagramNov 6, 2025

Every woman with PCOS I’ve ever tested has a homocysteine problem...

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Every woman with PCOS I’ve ever tested has a homocysteine problem... That’s what Dr. Dan Purser says — and it might explain why so many women with PCOS struggle with pain, inflammation, fatigue, and even kidney or blood pressure issues. Hom

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InstagramApr 1, 2025

If you’ve been told you have the MTRR gene mutation and struggle with fatigue, depression, or high homocysteine,…

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If you’ve been told you have the MTRR gene mutation and struggle with fatigue, depression, or high homocysteine, this might be your missing link. MTRR mutations can impair your body’s ability to make SAMe (S-adenosyl methionine)—a critical

FacebookJan 9, 2025

MTHFR: THE TERRIBLE - but what is the problem I see with MTHFR SNPs? Inflammation caused by homocysteine! If you…

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MTHFR: THE TERRIBLE - but what is the problem I see with MTHFR SNPs? Inflammation caused by homocysteine! If you have high homocysteine, you get high inflammatory cytokine release. The only way to balance it out is reduced glutathione and

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InstagramNov 10, 2024

High homocysteine levels can lead to inflammation, joint and muscle pain, and even shifting pain throughout the…

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High homocysteine levels can lead to inflammation, joint and muscle pain, and even shifting pain throughout the body. It’s also linked to birth defects and chronic kidney failure, and can raise blood pressure. Six genetic SNPs (like MTR, MT

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InstagramNov 6, 2024

Ever wondered how Homocysteine, MTHFR, and Glutathione are connected? Homocysteine is a highly inflammatory…

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Ever wondered how Homocysteine, MTHFR, and Glutathione are connected? Homocysteine is a highly inflammatory substance that triggers cytokine release in the body, fueling inflammation. It’s part of the methionine cycle, which links directly

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InstagramJul 6, 2023

The MTHFR gene is responsible for producing the MTHFR enzyme, which plays a vital role in the process of methylation…

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…he MTHFR enzyme, which plays a vital role in the process of methylation in our bodies. Methylation is a crucial biological procedure involved in DNA repair, immune function, mood balancing, and detoxification, among other processes. Mutati…

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Health BlogOct 2, 2026

Intracellular Glutathione vs. Serum Levels: How to Lower Inflammatory Cytokines Naturally

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Most doctors run standard serum blood tests, see a "normal" nutrient level, and send you home. But measuring floating nutrients in your liquid serum is like looking at the paint on a house to see if the plumbing works inside. After reviewing over 40,000 advanced intracellular vitamin lab panels, the truth is clear: intracellular glutathione vs serum levels tell two entirely different stories. Your serum can look completely fine while your cells are completely depleted of the master antioxidant needed to protect your life. The Cytokine Threat When methylation breaks down and homocysteine elevat

InstagramJul 11, 2026

Could an overlooked lab marker be providing valuable insight into your health?

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Could an overlooked lab marker be providing valuable insight into your health? Understanding your homocysteine level may help you and your healthcare provider identify opportunities to support cardiovascular health, healthy methylation, an

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FacebookJun 15, 2026

What if one overlooked lab marker is telling you more about your health than you realize?

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What if one overlooked lab marker is telling you more about your health than you realize? Most people have never heard of homocysteine. Yet when homocysteine levels are elevated, it may signal that critical pathways involving methylation,

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