Let’s explore “citric acid cycle”

DHFR helps reduce folic acid and dihydrofolate to tetrahydrofolate-related forms used in cellular metabolism. This is one part of the folate system, distinct from MTHFR and folate transport into cells.

Encodes an enzyme involved in fatty-acid metabolism.

Encodes an enzyme involved in fatty-acid metabolism.

Explore D-amino acid oxidase activator (DAOA / G72), rs2391191, D-serine, NMDA receptors, glutamate signaling, and research questions about brain and mood.

Explore hair shedding, the hair-growth cycle, telogen effluvium, nutrient deficiencies, and questions about changes during supplementation.

You eat something sweet. Your energy shoots up. Then suddenly you are exhausted, foggy, irritable, and reaching for something else to get you through the day. That cycle deserves a closer look. MTHFR variants can influence folate meta

Explore the reduced folate carrier (RFC1), rs3788200, rs1051266, intracellular folate, homocysteine, and folinic acid and methylfolate.

PURSER WELLNESSHow to Properly Treat Kids: Root Cause Medicine for Autism, ADHD, and Developmental ChallengesA conversation with Dr. Purser

In this powerful live session, Dr. Dan Purser MD reveals why conventional pediatric medicine often falls short and shares his proven Purser Method® for helping children with autism spectrum traits, severe ADHD, chronic inflammation, and developmental delays. Drawing from over 43 years of clinical experience, Dr. Purser explains: Why genetic testing (especially MTHFR and related SNPs) is the essential first step How to use targeted, active-form nutrients instead of generic vitamins The role of leucovorin (high-dose folinic acid) and when it makes a real difference Practical ways to reduce toxin load and calm the inflammatory response Smart strategies around vaccination and detoxification support Dr. Purser emphasizes that kids are not little adults — their developing systems need precise, individualized care. Parents and practitioners will walk away with actionable steps that address root causes rather than just managing symptoms. Whether your child is struggling with speech delays, meltdowns, focus issues, or recurrent health problems, this episode offers real hope through biochemistry done right. Resources Mentioned: Pediatric MTHFR formulas: https://www.PhysicianDesigned.com Book a consultation: http://www.DanPurserMD.com Dr. Purser’s books on Amazon: https://www.amazon.com/-/e/B00BIKSGVQ If you’re a parent tired of “there’s nothing more we can do,” or a practitioner looking for better tools, this episode is for you. Timestamps available in the full video. Subscribe, leave a review, and share this with any parent who needs to hear it. The kids deserve better answers. Dan Purser MD – Root Cause Inflammation & Genetic Optimization #MTHFR #Autism #ADHD #ChildrensHealth #Leucovorin #FunctionalMedicine #Pediatrics Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSTreat Root Cause Symptoms?A conversation with Dr. Purser

Tired, foggy, low hormones, and nothing helps? It’s probably not magic—it’s nutrient deficiency. Dr. Purser uses CMA with Redox testing to go deeper than your average doctor ever will. He sees severe lipoic acid, biotin, PQQ, and lithium deficiencies causing symptoms that mimic dementia, thyroid issues, or low testosterone. It’s not “manopause”—it’s vitaminopause. Find the root cause, don’t just chase prescriptions.

PURSER WELLNESSVARS Glutathione - How to UseA conversation with Dr. Purser

Dr. Purser explains how glutathione works, how to use the product, and how much to use. Explore the antioxidant similarities of glutathione to Vitamin C (ascorbic acid) such as antiviral properties, blood vessel health, bone health, and support of hormone production. Discover how CD4 and CD8 T-killer white blood cells rely on glutathione to provide immunity and remove viruses, toxins, and lactic acid from the body. Learn how Metallothionein requires glutathione to complete the functioning molecule that removes heavy metals from the bloodstream. Discover the mental clarity and well-being that c

PURSER WELLNESSWhat is Glutathione?A conversation with Dr. Purser

Dr. Purser shares facts about glutathione. Learn about tripeptide amino acids. Discover information on glutathione from the National Institutes of Health (NIH) and the Food and Drug Administration (FDA). Learn the definition of VARS (Validated, Absorbable, Reduced, and Stable) and why glutathione needs to have all these to work properly. Explore the antioxidant similarities of glutathione to Vitamin C (ascorbic acid) such as antiviral properties, blood vessel health, bone health, and support of hormone production. Learn how CD4 and CD8 T-killer white blood cells rely on glutathione to provide

🚨 High homocysteine isn’t just a lab number—it’s a warning sign. Genes like MTHFR, MTR, MTRR, and GGH can overactivate the methylation cycle and lead to hyperhomocysteinemia, which drives inflammation, stroke risk, and even kidney failure.