TPSAB1
Some search terms matched…y see TPSAB1 discussed alongside MCAS, Histamine, Mast cell signaling. These are topics to explore, not a diagnosis or a measurement of how the pathway works in your body.
Understanding a result
A gene name is only a starting point. Check w…
IL-23R & liver health
Some search terms matched…nderstand the connection
Dr. Purser explores IL-23 and Th17 signaling in fatty liver disease and inflammatory liver conditions. Older terms NAFLD and NASH appear alongside the newer terms MASLD and MASH.
Follow the pathway
This teaching fo…
IL-6 & liver health
Some search terms matched…ss, and treatment research.
Understand the connection
IL-6 signaling intersects with metabolism, insulin resistance, and inflammatory responses in the liver. Fatty liver disease can progress to inflammation and scarring in some people.
Fo…
Tourette syndrome & tic disorders
Some search terms matched…al-thalamo-cortical circuits, dopamine, and inhibitory GABA signaling. He also explores behavioral therapy, medicines, and selected specialist interventions rather than reducing tics to one gene or nutrient.
Bring these questions to your v…
CCL11 / Eotaxin-1
Some search terms matched…also called eotaxin-1, guides eosinophils toward tissues by signaling through CCR3. Eosinophils are immune cells involved in allergies and defense against some parasites.
Follow the pathway
Dr. Purser connects eosinophil recruitment with a…
CCL13 / MCP-4
Some search terms matched… inflammation and discusses the relationship between immune signaling and oxidative stress.
Bring these questions to your visit
Ask which result is being discussed: a genetic variant, a measured protein level, or a diagnosed condition. How…
CCL2 / MCP-1
Some search terms matched…nd metabolic inflammation. He discusses homocysteine, NF-κB signaling, and reactive oxygen species as interacting parts of this picture, alongside glutathione, superoxide dismutase, and catalase.
Bring these questions to your visit
Ask whi…
CCL3 / MIP-1 alpha
Some search terms matched… inflammatory joint damage. His teaching also connects CCL3 signaling with oxidative stress and the antioxidant network.
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Ask which result is being discussed: a genetic variant, a measured protein level, …
CD40 & immune-cell communication
Some search terms matched…e system.
Follow the pathway
Dr. Purser follows CD40–CD40L signaling into antibody responses, immune activation, and inflammation. He discusses the difference between a useful short-lived response and signaling that continues to affect hea…
IFNG rs2069705
Some search terms matched…Th1 immune pathway, macrophage activation, and inflammatory signaling. The exact allele and testing method matter when discussing a result, and an association does not establish disease.
Bring these questions to your visit
Ask which result…
IFNG rs2430561
Some search terms matched…rent meanings.
Follow the pathway
Dr. Purser follows IFN-γ signaling into T-cell and macrophage activity and the relationship between inflammation and oxidative stress. A genotype needs to be considered alongside measured findings and symp…
IL-13 & genetic variants
Some search terms matched…derstand the connection
IL-13 participates in type 2 immune signaling, including mucus production, allergic inflammation, and changes in barrier tissues. It works closely with IL-4 but is a distinct signal.
Follow the pathway
Dr. Purser co…
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