THE PURSER WELLNESS ENCYCLOPEDIA

Let’s explore “DHEA-S — lab reference”

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Gene referenceSep 23, 2026

MTHFR

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Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency. Also called: Methylenetetrahydrofolate Reductase, C677T, A1298C…

Gene referenceSep 23, 2026

MTRR

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Helps maintain the activity of methionine synthase, connecting B12-related chemistry with homocysteine metabolism. Also called: Methionine Synthase Reductase Keeping the remethylation system working Dr. Purser teaches MTRR alongside MTR bec…

Gene referenceSep 23, 2026

NOS3

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NOS3 encodes endothelial nitric oxide synthase, which helps blood vessels generate nitric oxide, a signal involved in vascular relaxation. This pathway is distinct from a blood pressure measurement or a diagnosis of vascular disease. Also c…

Gene referenceSep 23, 2026

NQO1

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NQO1 is the gene name for NAD(P)H Quinone Oxidoreductase 1. Learn what a specific result could mean and what to ask about it. Also called: NAD(P)H Quinone Oxidoreductase 1 Quinone handling within the redox network Dr. Purser includes NQO1 i…

Gene referenceSep 23, 2026

NR3C2

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NR3C2 encodes the mineralocorticoid receptor, which responds to hormones such as aldosterone and helps regulate salt and fluid balance. It is distinct from the NR3C1 glucocorticoid receptor. Also called: Mineralocorticoid Receptor / Nuclear…

Gene referenceSep 23, 2026

SERPINE1

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SERPINE1 makes PAI-1, a protein involved in breaking down blood clots. You may also see PAI4G used for this pathway. Also called: PAI-1, PAI4G, Plasminogen Activator Inhibitor-1, Plasminogen Activator Inhibitor 1, 4G/5G Polymorphism Balanci…

Gene referenceSep 23, 2026

SHMT1

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SHMT1 connects serine and glycine with folate chemistry. Also called: Serine Hydroxymethyltransferase 1 Where amino acids meet folate SHMT1 connects serine and glycine with folate pathways. That is one reason both nutrition and genetics can…

Gene referenceSep 23, 2026

TNF

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TNF encodes tumor necrosis factor, an immune-signaling protein involved in inflammation, host defense and regulation of cell survival. Its name should not be read as proof that a TNF result indicates cancer. Also called: Tumor Necrosis Fact…

Gene referenceSep 23, 2026

VDR

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VDR encodes the vitamin D receptor, which helps regulate gene activity in response to active vitamin D. A receptor variant does not by itself mean receptors are absent or that the blood vitamin D level is low. Also called: Vitamin D Recepto…

Gene referenceSep 23, 2026

CCL11

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CCL11 encodes eotaxin-1, a chemokine best known for attracting eosinophils. Its receptor relationships connect it to allergic inflammation as well as broader research into immune signaling. Also called: Eotaxin-1 and eosinophil recruitment…

Gene referenceSep 23, 2026

CCL2

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CCL2 encodes MCP-1, a chemokine that attracts monocytes toward sites of immune activity. Recruitment is a different task from the cytokines that activate those cells once they arrive. Also called: MCP-1: recruiting monocytes CCL2 encodes M…

Gene referenceSep 23, 2026

CCL4

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CCL4 encodes MIP-1 beta, a chemokine involved in attracting immune cells. It participates in a recruitment network that includes CCL2, CXCL8 and related chemokines. Also called: MIP-1 beta and overlapping recruitment signals CCL4 encodes M…

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