Let’s explore “C3 complement: deficiency and overactivation are different”

…lled: Vitamin D A nutrient level and a receptor gene answer different questions Dr. Purser places vitamin D in immune, hormone and bone-related teaching. The conversion-genetics chapter includes VDR, which concerns the vitamin D receptor. T…

… more than a question of folate intake. Rare inherited AHCY deficiency is different from most common variants. Seeing AHCY on a report does not prove that SAH is building up or that you have a rare disorder. A question to bring to your visi…

…d neurological context. Rare pathogenic FOLR1 disorders are different from the common markers in a wellness panel. A marker alone does not establish cerebral folate deficiency or select folinic-acid treatment; a neurological concern needs i…

… TCN2, MTHFD1, MTHFD1L, SLC19A1, CBS, and CTH. Each plays a different role. A gene name alone does not tell you whether a variant affects your health. Your exact result and its clinical classification matter. Common variants are different …

…es involved in that process. This developmental disorder is different from an acquired nutrient deficiency or a methylation result. Bring these questions to your visit Ask how the diagnosis has been confirmed and what specialist bowel care…

…clotting factor XI, part of the clotting cascade. Factor XI deficiency can cause a bleeding disorder, while other variants are studied in relation to higher clotting activity. Follow the pathway Dr. Purser discusses rs2289252, factor XI ac…

PURSER WELLNESSLow Testosterone and Vitamin DeficienciesFrom the reading room

…tracell™ Comprehensive Micronutrient Panel that looks at 39 different vitamins, minerals, and amino acids. However, Spectracell goes a step further as it looks inside your cells and gives us intracellular levels. The test is FDA- and HHS-ap…

…health outcome. A marker, a mechanism and an outcome Three different questions run through the history in this discussion. A marker is something researchers can measure, such as blood homocysteine. A mechanism is an explanation for how it …

…used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency. Topics: homocysteine, hyperhomocysteinemia, remethylation, transsulfuration, methionine, folate, B12, B6, kidney f…

…a variant is a particular difference in those instructions. Different variants in the same gene can have very different significance. “Homozygous” describes having the same variant in both copies at a location; it is not a severity score. M…

…evel. In particular, the usual association of B12 or folate deficiency is with higher homocysteine. Keep in mind Folate, B12, and B6 deficiencies more commonly raise homocysteine. A low result alone does not diagnose malnutrition or prove …

…used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency. Topics: homocysteine, monocytes, IL-8, CXCL8, MCP-1, CCL2, NF-kB, oxidative stress How these immune signals may c…