TNF
Some search terms matchedTNF encodes tumor necrosis factor, an immune-signaling protein involved in inflammation, host defense and regulation of cell survival. Its name should not be read as proof that a TNF result indicates cancer.
Also called: Tumor Necrosis Fact…
VKORC1
Some search terms matchedVKORC1 encodes vitamin K epoxide reductase, part of the vitamin K recycling system used in activating clotting proteins. It is not simply a vitamin K receptor.
Also called: Vitamin K Epoxide Reductase Complex Subunit 1
Recycling vitamin K a…
Understanding a nutrient deficiency
Some search terms matchedHow the Purser approach moves from a nutrient finding to priorities, a manageable plan and reassessment.
Also called:
From a laboratory flag to a useful plan
Start with your original CMA report: check its date, values, and the lab’s catego…
Homocysteine and methylation
Some search terms matchedFollow Dr. Purser’s teaching on folate, B12, sulfur pathways and antioxidant support around homocysteine.
Also called:
Follow the branches around homocysteine
Homocysteine sits at a junction in the pathway. Dr. Purser’s teaching follows ho…
How to read a laboratory report
Some search terms matchedSeparate the gene, variant, measured value and clinical interpretation—and learn which questions to bring to your visit.
Also called:
Keep the original result in view
Start with your original report: check the date, units, the lab’s range,…
SLC19A1
Some search terms matchedEncodes the reduced folate carrier, a protein involved in transporting folates into cells.
Also called: RFC1, reduced folate carrier, folate transport
Folate transport is part of the story
Dr. Purser’s folate map includes transport as well …
ALPL
Some search terms matchedALPL encodes tissue-nonspecific alkaline phosphatase, an enzyme important to bone and tooth mineralization and vitamin B6 metabolism. Persistently low alkaline phosphatase can deserve a different evaluation from a general nutrient deficienc…
CCL11
Some search terms matchedCCL11 encodes eotaxin-1, a chemokine best known for attracting eosinophils. Its receptor relationships connect it to allergic inflammation as well as broader research into immune signaling.
Also called:
Eotaxin-1 and eosinophil recruitment…
CCL2
Some search terms matchedCCL2 encodes MCP-1, a chemokine that attracts monocytes toward sites of immune activity. Recruitment is a different task from the cytokines that activate those cells once they arrive.
Also called:
MCP-1: recruiting monocytes
CCL2 encodes M…
CCL3
Some search terms matchedCCL3 encodes MIP-1 alpha, a chemokine involved in attracting and activating immune cells. It is related to CCL4, or MIP-1 beta, but the two genes and proteins are distinct.
Also called:
MIP-1 alpha and the chemokine cluster
CCL3 encodes MI…
CCL4
Some search terms matchedCCL4 encodes MIP-1 beta, a chemokine involved in attracting immune cells. It participates in a recruitment network that includes CCL2, CXCL8 and related chemokines.
Also called:
MIP-1 beta and overlapping recruitment signals
CCL4 encodes M…
CCL5
Some search terms matchedCCL5, also called RANTES, is a chemokine that helps direct immune-cell movement. Chemokines tell cells where to go, which is different from measuring the total strength of an immune response.
Also called:
RANTES and immune-cell recruitment…
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