Kidney disease has many possible causes.
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Kidney disease has many possible causes. Inflammation can participate in injury, but glucose, blood pressure, infection, obstruction, medicines, and other processes also ne…
Mesothelioma is a cancer that requires specialist diagnosis and treatment.
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Mesothelioma is a cancer that requires specialist diagnosis and treatment. The tumor environment includes immune and inflammatory processe…
Dr. Purser’s report looks at the immune signals involved in inflammation of the colon.
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Ulcerative colitis is an inflammatory bowel disease affecting the colon. Diagnosis and disease activity require a combination …
Explore the eye inflammation and cytokine connections in Dr. Purser’s report.
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Uveitis is inflammation inside the eye. The cause may involve immune disease, infection, or another process, so an eye examination is e…
Explore immune signaling in the context of autoimmune thyroid disease.
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Hashimoto’s thyroiditis is an autoimmune thyroid condition. Immune activity and thyroid hormone function are connected, but they are not inter…
Explore the role of type V collagen in connective tissue.
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COL5A1 helps make type V collagen, part of the scaffolding that organizes connective tissue. Pathogenic variants can be involved in classical Ehlers-Danlos…
Go beyond calcium in Dr. Purser’s discussion of mineral status.
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Bone mineral is built largely from calcium and phosphorus, while magnesium and other nutrients help regulate the processes that maintain bone. Bone s…
Learn why bone also needs a protein framework.
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Bone contains a protein scaffold as well as minerals. Amino acids supply the building blocks for collagen and other proteins that contribute to strength.
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Follow Dr. Purser’s explanation of how cells respond to insulin.
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The insulin receptor helps cells respond to insulin. After insulin binds, the receptor activates a chain of signals that influences glucose uptake a…
Adenomyosis involves uterine muscle and may cause pain and heavy bleeding.
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Adenomyosis occurs when tissue similar to the uterine lining is present within the uterine muscle. It can be associated with heavy bleedin…
Lichen planus can affect skin, mouth, nails, and other surfaces.
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Lichen planus is an inflammatory condition that can affect skin, the mouth, nails, and other surfaces. Examination helps distinguish it from similar…
Proctitis is inflammation of the rectal lining and has several possible causes.
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Proctitis means inflammation of the rectal lining. Inflammatory bowel disease, infection, radiation, and other causes can produce dif…
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